Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 3/20 | 0.36 |
| ▸ | HTR1D | P28221 | 2/20 | 0.36 |
| ▸ | HTR1B | P28222 | 2/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984002 | 0.84 | CHRNB2 (0.51) | RAPGEF4CHRNB2CHRNA7CHRNA4KMT2A | |
| SCHEMBL19984000 | 0.80 | HTR2A (0.46) | CFTRCHRNB2CHRNA7CHRNA4HTR1A | |
| SCHEMBL19984119 | 0.79 | GPR84 (0.53) | CHRNB2CHRNA7CHRNA4HTR1AHTR6 | |
| SCHEMBL19984216 | 0.78 | GPR84 (0.48) | CFTRCHRNB2CHRNA7CHRNA4HTR1A | |
| SCHEMBL19983831 | 0.77 | HTR2A (0.49) | HTR6KDM4EALDH1A1HTR2AKMT2A | |
| SCHEMBL19984088 | 0.77 | HTR1D (0.50) | CHRNB2CHRNA7CHRNA4HTR1AHTR1D | |
| SCHEMBL19983833 | 0.77 | SCN9A (0.44) | CHRNB2CHRNA7CHRNA4HTR1AKDM4E | |
| SCHEMBL19983845 | 0.76 | TBXAS1 (0.44) | KIF11CHRNB2CHRNA7CHRNA4HTR1A | |
| SCHEMBL19984001 | 0.75 | MAPK8 (0.48) | CFTRCHRNB2CHRNA7CHRNA4HTR1A | |
| SCHEMBL19983762 | 0.75 | MAPT (0.42) | CHRNB2CHRNA7CHRNA4KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |