Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 6/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.33 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CLK1 | P49759 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984027 | 0.87 | MAPK14 (0.37) | MAPK14CYP2D6FGFR2DDR1DDR2 | |
| SCHEMBL19983844 | 0.83 | ALDH1A1 (0.35) | MAPK14FGFR2CSF1RKITMEN1 | |
| SCHEMBL19984022 | 0.82 | AKR1C3 (0.38) | MAPK14FGFR2MAPTPOLB | |
| SCHEMBL19983777 | 0.82 | ADRB2 (0.37) | MAPK14NPC1RAB9A | |
| SCHEMBL19983907 | 0.80 | FPR1 (0.36) | MAPK14CYP2D6SLC6A4MEN1MAPT | |
| SCHEMBL16626473 | 0.78 | HTR6 (0.46) | — | |
| Hydrochloric Acid SCHEMBL16619180 | 0.77 | HTR6 (0.45) | HTR2A | |
| SCHEMBL16626731 | 0.76 | HTR6 (0.44) | MAPK14CYP2D6HTR2A | |
| Hydrochloric Acid SCHEMBL16619411 | 0.76 | HTR6 (0.46) | MAPK14CYP2D6HTR2A | |
| SCHEMBL19984025 | 0.75 | MAPK14 (0.32) | MAPK14MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |