Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 6/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.31 |
| ▸ | FBP1 | P09467 | 2/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.31 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.31 |
| ▸ | GAK | O14976 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983777 | 0.94 | ADRB2 (0.37) | MAPK14FBP1GAK | |
| SCHEMBL19983907 | 0.93 | FPR1 (0.36) | MAPK14CYP2D6MEN1KMT2AMAPT | |
| SCHEMBL19984022 | 0.92 | AKR1C3 (0.38) | MAPK14MAPTPOLBFGFR2AKR1C3 | |
| SCHEMBL19983844 | 0.89 | ALDH1A1 (0.35) | MAPK14MEN1KMT2AMAPTPOLB | |
| SCHEMBL19984025 | 0.89 | MAPK14 (0.32) | MAPK14MTNR1AMTNR1BMAPT | |
| SCHEMBL19984024 | 0.87 | MAPK14 (0.38) | MAPK14CYP2D6MEN1KMT2AMAPT | |
| SCHEMBL19983885 | 0.85 | FBP1 (0.39) | MAPK14FBP1GAK | |
| SCHEMBL19984021 | 0.84 | GAK (0.40) | MAPK14CYP2D6MEN1KMT2APOLB | |
| SCHEMBL19984271 | 0.84 | HTR2A (0.34) | MAPK14MEN1KMT2AMAPTPOLB | |
| SCHEMBL19983901 | 0.84 | TSHR (0.35) | MEN1KMT2AMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |