Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.38 |
| ▸ | GAK | O14976 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | SLC20A2 | Q08357 | 1/20 | 0.32 |
| ▸ | SLC20A1 | Q8WUM9 | 1/20 | 0.32 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984027 | 0.92 | MAPK14 (0.37) | AKR1C3AKR1C2GAKMAPK14POLB | |
| SCHEMBL19983777 | 0.89 | ADRB2 (0.37) | GAKADRB2MAPK14 | |
| SCHEMBL19983937 | 0.88 | MPO (0.37) | APPPOLBMAPTALDH1A1 | |
| SCHEMBL19983791 | 0.86 | KDR (0.33) | AKR1C3AKR1C2GAKKDRADRB2 | |
| SCHEMBL19984021 | 0.86 | GAK (0.40) | AKR1C3AKR1C2GAKKDRAPP | |
| SCHEMBL19983907 | 0.85 | FPR1 (0.36) | KDRMAPK14POLBMAPTALDH1A1 | |
| SCHEMBL19983844 | 0.84 | ALDH1A1 (0.35) | MAPK14GSK3BPOLBMAPTFGFR2 | |
| SCHEMBL19984024 | 0.82 | MAPK14 (0.38) | MAPK14POLBMAPTFGFR2 | |
| SCHEMBL19984029 | 0.82 | APP (0.35) | AKR1C3AKR1C2APPMAPT | |
| SCHEMBL16626503 | 0.81 | HTR6 (0.43) | AKR1C3AKR1C2MAPTAXLSLC20A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |