Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.33 |
| ▸ | MAT2A | P31153 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | VNN1 | O95497 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 2/20 | 0.32 |
| ▸ | XBP1 | P17861 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984022 | 0.88 | AKR1C3 (0.38) | MAPTAPPALDH1A1POLB | |
| SCHEMBL19984163 | 0.87 | FADS1 (0.36) | MPOMAPTP2RX3SLC6A4KCNH2 | |
| SCHEMBL19984029 | 0.86 | APP (0.35) | MPOMAPTAPPP2RX3SLC6A4 | |
| SCHEMBL19983907 | 0.86 | FPR1 (0.36) | MAPTSLC6A4KCNH2HTR2ACYP1A2 | |
| SCHEMBL19983888 | 0.85 | P2RX7 (0.31) | SLC6A4KCNH2CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL19984127 | 0.84 | NUDT1 (0.36) | SLC6A4KCNH2CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL19984021 | 0.81 | GAK (0.40) | APPSLC6A4KCNH2HTR2ACYP1A2 | |
| SCHEMBL19984271 | 0.81 | HTR2A (0.34) | MAPTSLC6A4KCNH2HTR2AEGFR | |
| SCHEMBL19983909 | 0.81 | SLC6A2 (0.35) | SLC6A4KCNH2HTR2ASLC6A2KDM4E | |
| SCHEMBL19984114 | 0.81 | CYP1A2 (0.31) | CYP1A2CYP2D6CYP2C9CYP2C19CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |