Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984203 | 0.83 | ABL1 (0.35) | MKNK2P2RX7 | |
| SCHEMBL16626487 | 0.82 | HTR6 (0.39) | MKNK2CNR1CNR2 | |
| Hydrochloric Acid SCHEMBL16619661 | 0.81 | HTR6 (0.39) | MKNK2CNR1CNR2 | |
| SCHEMBL19983916 | 0.80 | KDM4E (0.30) | — | |
| SCHEMBL19984009 | 0.79 | ALPL (0.37) | BACE2 | |
| SCHEMBL19984181 | 0.79 | TRPV1 (0.30) | — | |
| SCHEMBL19983777 | 0.79 | ADRB2 (0.37) | ADRB2P2RX7 | |
| SCHEMBL19983844 | 0.79 | ALDH1A1 (0.35) | CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL19984007 | 0.78 | MAT2A (0.34) | CYP11B1CYP11B2DHODHP2RX7 | |
| SCHEMBL19983981 | 0.78 | CNR2 (0.34) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |