SCHEMBL19984934

SCHEMBL19984934

CCOC(=O)/C(=C/OC1OC(=O)C(C)=C1C)C1COc2ccccc21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
MGAM O43451 1/20 0.35
AMY1A P0DUB6 1/20 0.35
GAA P10253 1/20 0.35
SI P14410 1/20 0.35
MGAM2 Q2M2H8 1/20 0.35
MEN1 O00255 4/20 0.35
KMT2A Q03164 4/20 0.35
MAPT P10636 2/20 0.35
ALDH1A1 P00352 1/20 0.35
TP53 P04637 1/20 0.35
ALOX15 P16050 1/20 0.35
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HSD17B10 Q99714 1/20 0.35
GLS O94925 2/20 0.35
CASP3 P42574 2/20 0.34
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19985035 0.90 MGAM (0.34) TSHRNPSR1L3MBTL1MGAMAMY1A
SCHEMBL23877355 0.88 GLS (0.33) MEN1KMT2AALDH1A1GLSKDM4E
SCHEMBL21538699 0.82 L3MBTL1 (0.36) TSHRNPSR1L3MBTL1MEN1KMT2A
SCHEMBL19984922 0.82 PIN1 (0.37) L3MBTL1MAPTALDH1A1POLBACKR3
SCHEMBL21538720 0.80 ANO1 (0.37) MEN1KMT2AMAPTALDH1A1TP53
SCHEMBL19985043 0.80 HPGD (0.36) MEN1KMT2AALDH1A1TP53HSD17B10
SCHEMBL21538741 0.79 GLS (0.41) TSHRNPSR1L3MBTL1MGAMAMY1A
SCHEMBL21538772 0.79 SIGMAR1 (0.33) TSHRL3MBTL1MAPTALDH1A1MAPK1
SCHEMBL21538716 0.78 FFAR1 (0.35) NPSR1L3MBTL1MGAMAMY1AGAA
SCHEMBL23877361 0.78 PTGDR2 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3512843-B1 PLANT GROWTH REGULATOR COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2021-10-20 EP disclosed
US-11136292-B2 Plant growth regulator compounds SYNGENTA PARTICIPATIONS AG (CH) 2021-10-05 US disclosed
US-20190330148-A1 PLANT GROWTH REGULATOR COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2019-10-31 US disclosed
WO-2018050477-A1 PLANT GROWTH REGULATOR COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2018-03-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11136292-B2 Plant growth regulator compounds FGF1, MST1, CDC20 TSHR 455/4885NPSR1 572/4885L3MBTL1 3472/4885
US-20190330148-A1 PLANT GROWTH REGULATOR COMPOUNDS FGF1, MST1, CDC20 TSHR 455/4885NPSR1 572/4885L3MBTL1 3472/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.