Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.38 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | PNLIP | P16233 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3564476 | 0.85 | P2RX3 (0.58) | P2RX3MAOBKMT2AMEN1EGLN1 | |
| SCHEMBL18529453 | 0.82 | LIPE (0.44) | MAOAMAOBKMT2AMEN1MAPT | |
| SCHEMBL20006725 | 0.82 | ALDH1A1 (0.45) | P2RX3KMT2AMEN1EGLN1MAPT | |
| SCHEMBL19994245 | 0.80 | PKM (0.43) | P2RX3KMT2AMEN1EGLN1MAPT | |
| SCHEMBL16025487 | 0.78 | POLB (0.51) | KMT2AMEN1MAPTRAB9ANPC1 | |
| SCHEMBL19808909 | 0.76 | TUBB4A (0.51) | P2RX3EGLN1L3MBTL1LMNA | |
| SCHEMBL28865211 | 0.74 | MCL1 (0.47) | P2RX3KMT2AMEN1EGLN1LMNA | |
| SCHEMBL19808853 | 0.74 | P2RX3 (0.48) | P2RX3KMT2AMEN1EGLN1MAPT | |
| SCHEMBL19808901 | 0.74 | P2RX3 (0.48) | P2RX3KMT2AMEN1EGLN1MAPT | |
| SCHEMBL19994248 | 0.73 | LMNA (0.48) | P2RX3MAPTHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190281828-A1 | NOVEL TRIAZOLE DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-09-19 | — | — | US | disclosed |
| US-20190281828-A1 | NOVEL TRIAZOLE DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-09-19 | — | — | US | disclosed |
| EP-3515906-A1 | NOVEL TRIAZOLE DERIVATIVES AND THEIR USE AS FUNGICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2019-07-31 | — | — | EP | disclosed |
| WO-2018054829-A1 | NOVEL TRIAZOLE DERIVATIVES AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-03-29 | — | — | WO | disclosed |
| WO-2018054829-A1 | NOVEL TRIAZOLE DERIVATIVES AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190281828-A1 | NOVEL TRIAZOLE DERIVATIVES | CBR3, TH, PADI1 | P2RX3 876/4885MAOA 1056/4885MAOB 751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.