Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18529456 | 0.82 | ALDH1A1 (0.40) | ALDH1A1MAPK1HIF1AP2RX3GSK3B | |
| SCHEMBL19994239 | 0.82 | P2RX3 (0.45) | P2RX3MEN1KMT2AEGLN1L3MBTL1 | |
| SCHEMBL3564476 | 0.79 | P2RX3 (0.58) | ALDH1A1P2RX3MEN1KMT2AEGLN1 | |
| SCHEMBL19994248 | 0.79 | LMNA (0.48) | ALDH1A1P2RX3LMNAMAPTHTT | |
| SCHEMBL19994245 | 0.75 | PKM (0.43) | ALDH1A1P2RX3MEN1KMT2AEGLN1 | |
| SCHEMBL20006624 | 0.74 | ALDH1A1 (0.67) | ALDH1A1MAPK1HIF1AGSK3BMEN1 | |
| SCHEMBL28865211 | 0.72 | MCL1 (0.47) | ALDH1A1P2RX3MEN1KMT2AEGLN1 | |
| SCHEMBL15756687 | 0.71 | GSK3B (0.77) | ALDH1A1MAPK1HIF1AGSK3BKMT2A | |
| SCHEMBL19808909 | 0.71 | TUBB4A (0.51) | ALDH1A1P2RX3EGLN1L3MBTL1LMNA | |
| SCHEMBL18529459 | 0.70 | KDM4E (0.50) | ALDH1A1MAPK1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190281828-A1 | NOVEL TRIAZOLE DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-09-19 | — | — | US | disclosed |
| US-20190281828-A1 | NOVEL TRIAZOLE DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-09-19 | — | — | US | disclosed |
| WO-2018054829-A1 | NOVEL TRIAZOLE DERIVATIVES AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190281828-A1 | NOVEL TRIAZOLE DERIVATIVES | CBR3, TH, PADI1 | ALDH1A1 2043/4885MAPK1 2079/4885HIF1A 3038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.