Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20007694 | 0.86 | CYP3A4 (0.53) | TRPV4 | |
| SCHEMBL20003532 | 0.84 | ACLY (0.53) | TRPV4ACLY | |
| SCHEMBL20003506 | 0.81 | CYP19A1 (0.60) | TRPV4 | |
| SCHEMBL29355694 | 0.75 | TRPV4 (0.51) | TRPV4 | |
| SCHEMBL21144246 | 0.75 | TRPV4 (0.51) | TRPV4 | |
| SCHEMBL21144245 | 0.75 | TRPV4 (0.51) | TRPV4 | |
| SCHEMBL20003557 | 0.74 | TRPV4 (0.59) | TRPV4 | |
| SCHEMBL14034045 | 0.71 | CNR1 (0.55) | ACLY | |
| SCHEMBL20007281 | 0.71 | TRPV4 (0.52) | TRPV4 | |
| SCHEMBL20003613 | 0.71 | TRPV4 (0.55) | TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018055524-A1 | TRPV4 ANTAGONISTS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2018-03-29 | — | — | WO | disclosed |