Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31289295 | 1.00 | ABCG2 (0.55) | ABCG2MAPTCYP1A2GAARECQL | |
| SCHEMBL3364680 | 0.89 | ABCG2 (0.56) | ABCG2MAPTCYP1A2GAARECQL | |
| Methyl Nicotinate SCHEMBL30617262 | 0.85 | ALDH1A1 (0.58) | ABCG2MAPTCYP1A2GAARECQL | |
| SCHEMBL31688990 | 0.83 | BACE1 (0.43) | ABCG2MAPTCYP1A2GAARECQL | |
| SCHEMBL2001591 | 0.83 | ALDH1A1 (0.65) | ABCG2MAPTCYP1A2GAABACE1 | |
| SCHEMBL16099506 | 0.83 | MAPT (0.53) | ABCG2MAPTL3MBTL1BACE1ALDH1A1 | |
| SCHEMBL16880740 | 0.82 | HSD17B14 (0.51) | MAPTCYP1A2TP53BACE1HTT | |
| SCHEMBL4163337 | 0.82 | HSD17B14 (0.50) | ABCG2MAPTCYP1A2GAARECQL | |
| SCHEMBL4758774 | 0.82 | HTT (0.42) | ABCG2MAPTCYP1A2GAARECQL | |
| SCHEMBL262639 | 0.81 | BACE1 (0.50) | ABCG2CYP1A2IRAK4BACE1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115947720-B | Design, preparation and application of beta 3 adrenergic receptor anchoring probe | 南京师范大学 | 2024-03-29 | — | — | CN | claimed |
| CN-115947720-A | Design of beta 3 adrenergic receptor anchoring probe and preparation method and application thereof | 南京师范大学 | 2023-04-11 | — | — | CN | claimed |
| CN-114426534-B | Reversible fluorescent probe for detecting copper ions and preparation method thereof | 南京师范大学 | 2023-01-31 | — | — | CN | claimed |
| CN-114426534-A | Reversible fluorescent probe for detecting copper ions and preparation method thereof | 南京师范大学 | 2022-05-03 | — | — | CN | claimed |
| EP-4547658-A1 | WEE1 DEGRADING COMPOUNDS AND USES THEREOF | Bristol-Myers Squibb Company (US) | 2025-05-07 | — | — | EP | disclosed |
| CN-119325469-A | WEE1 degrading compounds and uses thereof | 百时美施贵宝公司 | 2025-01-17 | — | — | CN | disclosed |
| US-20250011365-A1 | ECHINOCANDIN-BASED DRUG, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shenzhen Sungening Biological Co., Ltd (CN) | 2025-01-09 | — | — | US | disclosed |
| US-12144816-B2 | Substituted indole Mcl-1 inhibitors | VANDERBILT UNIVERSITY (US) | 2024-11-19 | — | — | US | disclosed |
| EP-3152190-B1 | 18-20 MEMBER BI-POLYCYCLIC COMPOUNDS | HARO PHARMACEUTICAL INC (US) | 2024-07-31 | — | — | EP | disclosed |
| CN-116903706-B | Echinocandin medicine and preparation method and application thereof | 深圳市祥根生物有限公司 | 2024-05-17 | — | — | CN | disclosed |
| CN-115947720-B | Design, preparation and application of beta 3 adrenergic receptor anchoring probe | 南京师范大学 | 2024-03-29 | — | — | CN | disclosed |
| US-20240067632-A1 | WEE1 Degrading Compounds and Uses Thereof | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-02-29 | — | — | US | disclosed |
| US-20050239054-A1 | Method and compositions for identifying anti-HIV therapeutic compounds | GILEAD SCIENCES. INC. | 2005-10-27 | — | — | US | disclosed |
| US-20050209197-A1 | Cellular accumulation of phosphonate analogs of HIV protease inhibitor compounds | GILEAD SCIENCES, INC. | 2005-09-22 | — | — | US | disclosed |
| CN-1649885-A | Cellular Accumulation of Phosphonate Analogs of HIV Protease Inhibitor Compounds and Such Compounds | GILEAD SCIENCES INC (US) | 2005-08-03 | — | — | CN | disclosed |
| US-20050165049-A1 | Vanilloid receptor ligands and their use in treatments | AMGEN, INC. | 2005-07-28 | — | — | US | disclosed |
| WO-2005064008-A1 | METHOD AND COMPOSITIONS FOR IDENTIFYING ANTI-HIV THERAPEUTIC COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2005-07-14 | — | — | WO | disclosed |
| EP-1509537-A2 | CELLULAR ACCUMULATION OF PHOSPHONATE ANALOGS OF HIV PROTEASE INHIBITOR COMPOUNDS AND THE COMPOUNDS AS SUCH | GILEAD SCIENCES, INC. (US) | 2005-03-02 | — | — | EP | disclosed |
| WO-2003090690-A2 | CELLULAR ACCUMULATION OF PHOSPHONATE ANALOGS OF HIV PROTEASE INHIBITOR COMPOUNDS AND THE COMPOUNDS AS SUCH | GILEAD SCIENCES, INC. (US) | 2003-11-06 | — | — | WO | disclosed |
| CN-85100796-A | The preparation method of qualone derivative | — | 1986-10-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050165049-A1 | Vanilloid receptor ligands and their use in treatments | TRPV1, TRPV2, TRPV3 | ABCG2 836/4885MAPT 716/4885CYP1A2 2081/4885 |
| US-20050209197-A1 | Cellular accumulation of phosphonate analogs of HIV protease inhibitor compounds | PPA1, PPME1, PNP | ABCG2 922/4885MAPT 1039/4885CYP1A2 4452/4885 |
| US-20050239054-A1 | Method and compositions for identifying anti-HIV therapeutic compounds | CES1, PNP, PGLS | ABCG2 203/4885MAPT 3202/4885CYP1A2 2040/4885 |
| US-12144816-B2 | Substituted indole Mcl-1 inhibitors | MCL1, BCL2L1, BCL9 | ABCG2 2827/4885MAPT 2996/4885CYP1A2 4125/4885 |
| US-20250011365-A1 | ECHINOCANDIN-BASED DRUG, AND PREPARATION METHOD THEREFOR AND USE THEREOF | CYP51A1, ERG28, WEE1 | ABCG2 81/4885MAPT 3876/4885CYP1A2 901/4885 |
| US-20240067632-A1 | WEE1 Degrading Compounds and Uses Thereof | WEE1, WEE2, PPME1 | ABCG2 4257/4885MAPT 2871/4885CYP1A2 3456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.