Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C3AR1 | Q16581 | 12/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042748 | 0.89 | NPC1 (0.49) | MEN1KMT2APOLB | |
| SCHEMBL20042690 | 0.88 | GFER (0.41) | MEN1KMT2ACHRM4 | |
| SCHEMBL20042750 | 0.83 | F2 (0.39) | MEN1KMT2A | |
| SCHEMBL20042830 | 0.83 | ME2 (0.43) | MEN1KMT2A | |
| SCHEMBL20042832 | 0.81 | CFTR (0.45) | MEN1KMT2AKDM4EPOLB | |
| SCHEMBL20042747 | 0.80 | GRIN1 (0.39) | PTGDR2KMT2A | |
| SCHEMBL20042888 | 0.80 | PTGDR2 (0.35) | PTGDR2CHRM4CYP1A2 | |
| SCHEMBL20042703 | 0.80 | PTGDR2 (0.37) | PTGDR2CHRM4CYP1A2 | |
| SCHEMBL20042673 | 0.78 | MAPK1 (0.38) | PTGDR2 | |
| SCHEMBL20042714 | 0.75 | CHRM4 (0.43) | KMT2ACHRM4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |