Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042830 | 0.88 | ME2 (0.43) | MEN1KMT2AMAPTNAAA | |
| SCHEMBL20042748 | 0.88 | NPC1 (0.49) | MEN1KMT2AMAPTNAAA | |
| SCHEMBL20042747 | 0.87 | GRIN1 (0.39) | KMT2AKCNQ2 | |
| SCHEMBL20042673 | 0.87 | MAPK1 (0.38) | MAPK1 | |
| SCHEMBL20042703 | 0.85 | PTGDR2 (0.37) | — | |
| SCHEMBL20042688 | 0.83 | C3AR1 (0.45) | MEN1KMT2A | |
| SCHEMBL20042690 | 0.83 | GFER (0.41) | LMNAMEN1KMT2ANAAA | |
| SCHEMBL20042888 | 0.83 | PTGDR2 (0.35) | MAPT | |
| SCHEMBL20042771 | 0.81 | P2RX7 (0.47) | LMNAMEN1KMT2AMAPT | |
| SCHEMBL20042730 | 0.76 | NPC1 (0.48) | MEN1KMT2AMAPTNAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |