Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 4/20 | 0.43 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.36 |
| ▸ | MPL | P40238 | 1/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.34 |
| ▸ | GBA1 | P04062 | 3/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | MTHFD1 | P11586 | 1/20 | 0.34 |
| ▸ | MTHFD2 | P13995 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GPR6 | P46095 | 1/20 | 0.34 |
| ▸ | PRLHR | P49683 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042780 | 0.93 | P2RX7 (0.43) | P2RX7MAPK7GBA1MGLLGPR6 | |
| SCHEMBL20042765 | 0.88 | P2RX7 (0.42) | P2RX7MAPK7LRRK2MGLLHPGD | |
| SCHEMBL20042666 | 0.86 | KMT2A (0.46) | P2RX7GBA1CNR1CNR2GPR55 | |
| SCHEMBL20042705 | 0.85 | EPHX2 (0.45) | P2RX7MAPK7MGLLPRLHR | |
| SCHEMBL20042836 | 0.85 | P2RX7 (0.43) | P2RX7GBA1CNR1CNR2GPR55 | |
| SCHEMBL20042667 | 0.84 | TACR3 (0.46) | P2RX7TACR3 | |
| SCHEMBL20042823 | 0.83 | P2RX7 (0.45) | P2RX7GBA1CNR1CNR2GPR55 | |
| SCHEMBL20042754 | 0.82 | MEN1 (0.41) | P2RX7KDM4EHPGDTSHRCASP1 | |
| SCHEMBL20042792 | 0.82 | TACR3 (0.46) | P2RX7CNR1CNR2GPR55HPGD | |
| SCHEMBL20042861 | 0.81 | P2RX7 (0.39) | P2RX7MAPK7MGLLKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |