Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 4/20 | 0.43 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.36 |
| ▸ | PRLHR | P49683 | 2/20 | 0.35 |
| ▸ | GPR6 | P46095 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042694 | 0.93 | P2RX7 (0.43) | P2RX7MAPK7MGLLPRLHRGPR6 | |
| SCHEMBL20042765 | 0.90 | P2RX7 (0.42) | P2RX7MAPK7MGLLEPHX2GPR6 | |
| SCHEMBL20042917 | 0.87 | P2RX7 (0.39) | P2RX7GPR6 | |
| SCHEMBL20042666 | 0.86 | KMT2A (0.46) | P2RX7GBA1 | |
| SCHEMBL20042705 | 0.85 | EPHX2 (0.45) | P2RX7MAPK7MGLLEPHX2PRLHR | |
| SCHEMBL20042823 | 0.85 | P2RX7 (0.45) | P2RX7PRLHRGBA1 | |
| SCHEMBL20042792 | 0.84 | TACR3 (0.46) | P2RX7GPR6 | |
| SCHEMBL20042836 | 0.83 | P2RX7 (0.43) | P2RX7GBA1 | |
| SCHEMBL20042882 | 0.82 | P2RX7 (0.41) | P2RX7GPR6GBA1 | |
| SCHEMBL20042696 | 0.82 | KDM1A (0.45) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |