Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAM | P19021 | 2/20 | 0.63 |
| ▸ | CES1 | P23141 | 2/20 | 0.61 |
| ▸ | CES2 | O00748 | 1/20 | 0.61 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | FNTA | P49354 | 1/20 | 0.50 |
| ▸ | FNTB | P49356 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL905745 | 0.89 | PAM (0.53) | PAMCES1CES2AKR1B1L3MBTL1 | |
| SCHEMBL23258762 | 0.88 | PAM (0.52) | PAMCES1CES2AKR1B1L3MBTL1 | |
| SCHEMBL15574257 | 0.85 | PAM (0.63) | PAMCES1CES2AKR1B1L3MBTL1 | |
| SCHEMBL27546894 | 0.83 | PAM (0.61) | PAMCES1CES2AKR1B1L3MBTL1 | |
| SCHEMBL27988220 | 0.82 | PAM (0.66) | PAMCES1CES2AKR1B1L3MBTL1 | |
| SCHEMBL7324963 | 0.81 | PAM (0.59) | PAMCES1CES2AKR1B1L3MBTL1 | |
| SCHEMBL200593 | 0.81 | PAM (0.59) | PAMCES1CES2AKR1B1L3MBTL1 | |
| SCHEMBL3048336 | 0.79 | TDP1 (0.79) | PAMCES1CES2AKR1B1L3MBTL1 | |
| SCHEMBL28222699 | 0.79 | PAM (0.57) | PAMCES1CES2AKR1B1L3MBTL1 | |
| SCHEMBL28874611 | 0.79 | PAM (0.57) | PAMCES1CES2AKR1B1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1525 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4725950-A1 | IMPROVED SOLID-PHASE PHOSPHORAMIDITE-SYNTHESIS OF LONG OLIGONUCLEOTIDE MOLECULES | BioSpring Gesellschaft für Biotechnologie mbH (DE) | 2026-04-15 | — | — | EP | claimed |
| EP-4725949-A1 | IMPROVED SOLID-PHASE PHOSPHORAMIDITE-SYNTHESIS OF LONG OLIGONUCLEOTIDE MOLECULES | BioSpring Gesellschaft für Biotechnologie mbH (DE) | 2026-04-15 | — | — | EP | claimed |
| US-20260097383-A1 | SOLID-PHASE PHOSPHORAMIDITE-SYNTHESIS OF LONG OLIGONUCLEOTIDE MOLECULES | BioSpring Gesellschaft für Biotechnologie mbH (DE) | 2026-04-09 | — | — | US | claimed |
| US-12492220-B2 | Method for the preparation of oligonucleotides | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2025-12-09 | — | — | US | claimed |
| US-12435105-B2 | Technologies for oligonucleotide preparation | WAVE LIFE SCIENCES LTD. (SG) | 2025-10-07 | — | — | US | claimed |
| US-12264174-B2 | Process for preparing imetelstat | GERON CORPORATION (US) | 2025-04-01 | — | — | US | claimed |
| EP-4526944-A1 | THTOCARBONATE COMPOSITIONS FOR LITHIUM- SULFUR BATTERIES | Conamix Inc. (US) | 2025-03-26 | — | — | EP | claimed |
| CN-113631564-B | Method for producing oligonucleotide having phosphorothioate site | 味之素株式会社 | 2025-02-25 | — | — | CN | claimed |
| CN-114573652-B | Process for synthesizing medicinal nucleic acid | 安徽瑞拜药业有限公司 | 2025-02-07 | — | — | CN | claimed |
| EP-3475292-B1 | SYNTHESIS OF THIOLATED OLIGONUCLEOTIDES WITHOUT A CAPPING STEP | BIOGEN MA INC (US) | 2024-09-18 | — | — | EP | claimed |
| EP-1386925-A1 | Method for preparing oligonucleotides | Girindus AG (DE) | 2004-02-04 | — | — | EP | claimed |
| US-20030212267-A1 | Synthesis of sulfurized oligonucleotides | IONIS PHARMACEUTICALS, INC. | 2003-11-13 | — | — | US | claimed |
| EP-1246833-A4 | IMPROVED SYNTHESIS OF SULFURIZED OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS INC (US) | 2003-04-09 | — | — | EP | claimed |
| EP-1246833-A1 | IMPROVED SYNTHESIS OF SULFURIZED OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS, INC. (US) | 2002-10-09 | — | — | EP | claimed |
| WO-2001051502-A1 | IMPROVED SYNTHESIS OF SULFURIZED OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS, INC. (US) | 2001-07-19 | — | — | WO | claimed |
| US-6242591-B1 | Synthesis of sulfurized 2'-substituted oligonucleotides | ISIS PHARMACEUTICALS, INC. | 2001-06-05 | — | — | US | claimed |
| EP-1023310-A4 | IMPROVED SYNTHESIS OF SULFURIZED OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS INC (US) | 2001-05-16 | — | — | EP | claimed |
| US-6114519-A | PHOSPHITYLATION; OXIDATION ACYL DISULFIDE | ISIS PHARMACEUTICALS, INC. (US) | 2000-09-05 | — | — | US | claimed |
| EP-1023310-A1 | IMPROVED SYNTHESIS OF SULFURIZED OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS, INC. (US) | 2000-08-02 | — | — | EP | claimed |
| WO-1999019340-A1 | IMPROVED SYNTHESIS OF SULFURIZED OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS, INC. (US) | 1999-04-22 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260097383-A1 | SOLID-PHASE PHOSPHORAMIDITE-SYNTHESIS OF LONG OLIGONUCLEOTIDE MOLECULES | RNGTT, NSUN2, RNMT | PAM 1193/4885CES1 3414/4885CES2 3863/4885 |
| US-12435105-B2 | Technologies for oligonucleotide preparation | POLRMT, DCLRE1B, RNGTT | PAM 2030/4885CES1 2271/4885CES2 4249/4885 |
| US-12492220-B2 | Method for the preparation of oligonucleotides | POLN, POLRMT, POLI | PAM 2284/4885CES1 4524/4885CES2 4455/4885 |
| US-12264174-B2 | Process for preparing imetelstat | TERT, RNGTT, TRMT1L | PAM 1297/4885CES1 2380/4885CES2 3750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.