SCHEMBL20109957

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27010345	0.97	CA1 (0.38)	CA1CA2ENPP1GPR84CYP3A4
	SCHEMBL25575882	0.96	CA1 (0.42)	CA1CA2ENPP1GPR84KDM4E
	SCHEMBL19764761	0.95	CA1 (0.41)	CA1CA2ENPP1GPR84KDM4E
	SCHEMBL23426578	0.93	CA1 (0.38)	CA1CA2ENPP1GPR84KDM4E
	SCHEMBL21131864	0.93	CA1 (0.37)	CA1CA2GPR84KDM4EALDH1A1
	SCHEMBL23426751	0.91	CA1 (0.42)	CA1CA2KDM4EALDH1A1CYP3A4
	SCHEMBL20109945	0.90	PLA2G2A (0.37)	CA1CA2GPR84ALDH1A1CYP3A4
	SCHEMBL20109977	0.90	PLA2G2A (0.40)	CA1CA2GPR84CYP3A4HPGD
	SCHEMBL24481446	0.90	GPR84 (0.39)	CA1CA2ENPP1GPR84KDM4E
	SCHEMBL27010381	0.90	PLA2G2A (0.40)	CA1CA2GPR84KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.