Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 3/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NMT1 | P30419 | 3/20 | 0.34 |
| ▸ | NMT2 | O60551 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15759098 | 0.84 | ALDH1A1 (0.47) | ALDH1A1PKMNAMPTHPGDBCHE | |
| SCHEMBL11928030 | 0.81 | ALDH1A1 (0.45) | ALDH1A1NAMPTHPGDPRMT3USP2 | |
| SCHEMBL22735753 | 0.77 | LMNA (0.50) | ALDH1A1LMNAPKMNAMPTCNR1 | |
| SCHEMBL25925311 | 0.77 | MEN1 (0.45) | ALDH1A1PKMNAMPTHPGDPRMT3 | |
| SCHEMBL9891910 | 0.75 | SIGMAR1 (0.43) | ALDH1A1NAMPTBCHEPIK3CDCTSD | |
| SCHEMBL13070014 | 0.75 | ALDH1A1 (0.42) | ALDH1A1NAMPTPRMT3SMN1; SMN2 | |
| SCHEMBL13328249 | 0.74 | LMNA (0.60) | ALDH1A1LMNAPKMNAMPTCNR1 | |
| SCHEMBL18860301 | 0.74 | PIK3CD (0.44) | LMNAPKMHPGDPIK3CD | |
| SCHEMBL9893063 | 0.73 | BRD4 (0.43) | ALDH1A1NAMPTCNR2PRMT3 | |
| SCHEMBL21730473 | 0.72 | ITGB3 (0.43) | ALDH1A1NAMPTBCHESMN1; SMN2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180118754-A1 | COMPOUNDS | RESPIVERT LTD. (GB) | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118754-A1 | COMPOUNDS | LTC4S, CYP11B2, LTB4R2 | ALDH1A1 224/4885LMNA 1817/4885PKM 1053/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.