Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20113637 | 0.69 | GRM1 (0.32) | GRM1 | |
| SCHEMBL20113649 | 0.69 | MEN1 (0.37) | GRM1 | |
| SCHEMBL20113675 | 0.68 | ALDH1A1 (0.34) | GRM1 | |
| SCHEMBL20113671 | 0.67 | GLP1R (0.33) | GRM1 | |
| SCHEMBL20113669 | 0.64 | FGFR4 (0.40) | FGFR4 | |
| SCHEMBL16707007 | 0.63 | FPR2 (0.34) | — | |
| SCHEMBL20113662 | 0.62 | — | — | |
| SCHEMBL20113696 | 0.61 | MEN1 (0.36) | — | |
| SCHEMBL22365597 | 0.60 | NPSR1 (0.44) | — | |
| SCHEMBL12015724 | 0.59 | L3MBTL1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3060563-B1 | RING-FUSED BICYCLIC PYRIDYL DERIVATIVES AS FGFR4 INHIBITORS | NOVARTIS AG (CH) | 2018-05-02 | — | — | EP | disclosed |