Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | NR1I3 | Q14994 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | APP | P05067 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8325338 | 0.78 | KDM4E (0.74) | CYP1A2ALDH1A1HPGDL3MBTL1MEN1 | |
| SCHEMBL29532939 | 0.78 | KDM4E (0.74) | CYP1A2ALDH1A1HPGDL3MBTL1MEN1 | |
| SCHEMBL9587545 | 0.78 | KEAP1 (0.44) | CYP1A2ALDH1A1NUDT1HPGDHSD17B10 | |
| SCHEMBL11165369 | 0.77 | L3MBTL1 (0.56) | CYP1A2ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL377227 | 0.74 | HSD17B10 (1.00) | CYP1A2ALDH1A1NUDT1HPGDHSD17B10 | |
| SCHEMBL30080783 | 0.74 | HSD17B10 (1.00) | CYP1A2ALDH1A1NUDT1HPGDHSD17B10 | |
| SCHEMBL4572143 | 0.73 | NUDT1 (0.58) | CYP1A2ALDH1A1NUDT1HPGDHSD17B10 | |
| SCHEMBL10568650 | 0.73 | MAP3K5 (0.46) | CYP1A2NUDT1HPGDL3MBTL1MEN1 | |
| SCHEMBL29375878 | 0.73 | DCPS (1.00) | CYP1A2ALDH1A1NUDT1HPGDHSD17B10 | |
| SCHEMBL269636 | 0.73 | DCPS (1.00) | CYP1A2ALDH1A1NUDT1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10308617-B2 | Triazole benzamide derivatives and the compositions and methods of treatment regarding the same | An2H Discovery Limited (IE) | 2019-06-04 | — | — | US | disclosed |
| US-20180118697-A1 | TRIAZOLE BENZAMIDE DERIVATIVES AND THE COMPOSITIONS AND METHODS OF TREATMENT REGARDING THE SAME | NYSNOBIO IRELAND DAC (IE) | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118697-A1 | TRIAZOLE BENZAMIDE DERIVATIVES AND THE COMPOSITIONS AND METHODS OF TREATMENT REGARDING THE SAME | PINK1, ATG7, ADRM1 | CYP1A2 376/4885ALDH1A1 504/4885NUDT1 3323/4885 |
| US-10308617-B2 | Triazole benzamide derivatives and the compositions and methods of treatment regarding the same | PINK1, ATG7, ADRM1 | CYP1A2 376/4885ALDH1A1 504/4885NUDT1 3323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.