Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 13/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.45 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140202 | 0.81 | HTR7 (0.55) | HTR7ATM | |
| SCHEMBL20156931 | 0.80 | MTOR (0.51) | HTR7PARP1MTORRPTORMLST8 | |
| SCHEMBL20142823 | 0.78 | CYP46A1 (0.48) | HTR7MTORRPTORMLST8 | |
| SCHEMBL20157295 | 0.76 | MTOR (0.47) | P2RX7HTR7PARP1ATMMTOR | |
| SCHEMBL20140957 | 0.76 | GBA1 (0.44) | HTR7PARP1 | |
| SCHEMBL20142241 | 0.75 | MTOR (0.61) | HTR7MTORRPTORMLST8 | |
| SCHEMBL20139930 | 0.75 | MTOR (0.53) | HTR7MTORRPTORMLST8 | |
| SCHEMBL20140044 | 0.75 | MTOR (0.54) | HTR7PARP1MTORRPTORMLST8 | |
| SCHEMBL20140664 | 0.72 | MTOR (0.57) | HTR7PARP1MTORRPTORMLST8 | |
| SCHEMBL20156911 | 0.72 | KDM4E (0.55) | ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |