SCHEMBL201429

SCHEMBL201429

CCCCCCCCCCCCCCCCCC(=O)OC(=O)CCCCCCCCCCCCCCCCC(CCCCCCCC)CCCCCCCCCCCC

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.55
DGKA P23743 1/20 0.53
CYP3A4 P08684 1/20 0.53
TSHR P16473 1/20 0.53
ATM Q13315 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
MAPT P10636 2/20 0.52
MAPK1 P28482 1/20 0.52
ALDH1A1 P00352 2/20 0.49
PAM P19021 2/20 0.48
FFAR4 Q5NUL3 1/20 0.48
FFAR1 O14842 1/20 0.48
KDM4E B2RXH2 1/20 0.47
DUSP3 P51452 1/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28886958 0.96 CYP3A4 (0.58) LMNADGKACYP3A4TSHRATM
SCHEMBL21571461 0.93 LMNA (0.53) LMNADGKACYP3A4TSHRATM
SCHEMBL28560061 0.93 MAPT (0.50) LMNADGKACYP3A4TSHRATM
SCHEMBL28127070 0.93 MAPT (0.50) LMNADGKACYP3A4TSHRATM
SCHEMBL21571462 0.93 LMNA (0.53) LMNADGKACYP3A4TSHRATM
SCHEMBL8984419 0.91 MAPT (0.49) LMNADGKACYP3A4TSHRATM
SCHEMBL27747277 0.89 CYP3A4 (0.51) LMNADGKACYP3A4TSHRATM
SCHEMBL25438173 0.87 DGKA (0.67) LMNADGKATSHRTDP1MAPT
SCHEMBL21647233 0.87 DGKA (0.67) LMNADGKATSHRTDP1MAPT
SCHEMBL20529845 0.87 DGKA (0.67) LMNADGKATSHRTDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024096480-A1 SOLID COSMETIC COMPOSITION CONTAINING LARGE AMOUNT OF HYALURONIC ACID 코스맥스 주식회사 2024-05-10 WO claimed
WO-2007132971-A1 WATER-IN-OIL TYPE EMULSION LIQUID ROUGE COMPOSITION AMOREPACIFIC CORPORATION (KR) 2007-11-22 WO claimed
US-6589519-B1 Smoothness, softness; shampoo L'OREAL S.A. (FR) 2003-07-08 US claimed
EP-1009366-B1 COSMETIC COMPOSITIONS COMPRISING A POLYOXYALKYLATED AMINATED SILICONE BLOCK POLYMER AND A CONDITIONING AGENT AND THEIR USE OREAL (FR) 2003-03-26 EP claimed
US-5863546-A CREAM, LOTION, SHAMPOO, CLEANSERS OR POWDER MAKEUP SWINEHART JAMES M (US) 1999-01-26 US claimed
WO-2024096480-A1 SOLID COSMETIC COMPOSITION CONTAINING LARGE AMOUNT OF HYALURONIC ACID 코스맥스 주식회사 2024-05-10 WO disclosed
EP-3197937-B1 SILICONE COMPOUNDS AND COMPOSITIONS THEREOF FOR THE TREATMENT OF AMINO ACID BASED SUBSTRATES MOMENTIVE PERFORMANCE MAT GMBH (DE) 2024-04-24 EP disclosed
CN-116138562-A Stick-shaped cosmetic and preparation method thereof 克罗莫维斯股份公司 2023-05-23 CN disclosed
US-10702454-B2 Solid cosmetic composition in pressed powder form L'OREAL (FR) 2020-07-07 US disclosed
EP-2928448-B1 SOLID COSMETIC COMPOSITION IN PRESSED POWDER FORM OREAL (FR) 2019-08-21 EP disclosed
US-10266656-B2 Silicone compounds and compositions thereof for the treatment of amino acid based substrates MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) 2019-04-23 US disclosed
US-20170291994-A1 Silicone Compounds And Compositions Thereof For The Treatment Of Amino Acid Based Substrates CITIBANK, N.A., AS ADMINISTRATIVE AGENT 2017-10-12 US disclosed
US-20040131572-A1 Composition for treating keratinous materials comprising a cationic poly(alkyl) vinyllactam polymer and a protecting or conditioning agent L'OREAL (FR) 2004-07-08 US disclosed
US-20040037796-A1 Composition for treating keratinous materials comprising a cationic associative polyurethane polymer and a protecting or conditioning agent L'OREAL S.A. (FR) 2004-02-26 US disclosed
US-20030157049-A1 Cosmetic compositions containing a particular aminosilicone and a conditioner, and uses thereof L'OREAL S.A. (FR) 2003-08-21 US disclosed
US-20030147842-A1 Cosmetic compositions containing a particular aminosilicone and a conditioner, and uses thereof L'OREAL S.A. (FR) 2003-08-07 US disclosed
US-6589519-B1 Smoothness, softness; shampoo L'OREAL S.A. (FR) 2003-07-08 US disclosed
US-5928652-A BINDER HAVING ESTER AND FATTY SUBSTANCE L'OREAL (FR) 1999-07-27 US disclosed
US-5468401-A Carrier-free metalworking lubricant and method of making and using same CHEM-TREND, INCORPORATED (US) 1995-11-21 US disclosed
EP-0590959-A2 Carrier-free metalworking lubricant and method of making and using same CASTROL LIMITED (GB) 1994-04-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030147842-A1 Cosmetic compositions containing a particular aminosilicone and a conditioner, and uses thereof CUTA, KRT18, PRMT8 LMNA 1292/4885DGKA 1452/4885CYP3A4 3398/4885
US-20030157049-A1 Cosmetic compositions containing a particular aminosilicone and a conditioner, and uses thereof CUTA, KRT18, MARK1 LMNA 1368/4885DGKA 1155/4885CYP3A4 4316/4885
US-20040131572-A1 Composition for treating keratinous materials comprising a cationic poly(alkyl) vinyllactam polymer and a protecting or conditioning agent KRT18, CUTA, VCL LMNA 445/4885DGKA 677/4885CYP3A4 4818/4885
US-20040037796-A1 Composition for treating keratinous materials comprising a cationic associative polyurethane polymer and a protecting or conditioning agent KRT18, PUF60, FSCN1 LMNA 1732/4885DGKA 1741/4885CYP3A4 4868/4885
US-10266656-B2 Silicone compounds and compositions thereof for the treatment of amino acid based substrates BCAT2, CUTA, BCAT1 LMNA 1260/4885DGKA 2902/4885CYP3A4 2195/4885
US-10702454-B2 Solid cosmetic composition in pressed powder form CUTA, PLIN5, AUP1 LMNA 945/4885DGKA 2608/4885CYP3A4 4499/4885
US-20170291994-A1 Silicone Compounds And Compositions Thereof For The Treatment Of Amino Acid Based Substrates BCAT2, CUTA, BCAT1 LMNA 1260/4885DGKA 2902/4885CYP3A4 2195/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.