SCHEMBL201622

SCHEMBL201622

CCO[Si](CCCNC)(OC)OCC

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.34
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL111512 0.89 EPHX1 (0.39) EPHX1
SCHEMBL729887 0.85 CYP2C19 (0.33) LMNA
SCHEMBL56162 0.84 LMNA (0.38) EPHX1LMNA
SCHEMBL28897340 0.83 LMNA (0.32) LMNA
SCHEMBL24178934 0.83 LMNA (0.32) LMNA
SCHEMBL28540736 0.83 EPHX1 (0.39) EPHX1
SCHEMBL200380 0.83 EPHX1 (0.42) EPHX1
SCHEMBL9795663 0.82 LMNA (0.36) EPHX1LMNA
SCHEMBL6064085 0.82 LMNA (0.39) LMNA
SCHEMBL15327667 0.81 CYP2C19 (0.33) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9795694-B2 Imaging beta-amyloid peptides aggregation HONG KONG BAPTIST UNIVERSITY (HK) 2017-10-24 US disclosed
EP-2142558-B1 HYDROLYZABLE SILANES OF LOW VOC-GENERATING POTENTIAL AND RESINOUS COMPOSITIONS CONTAINING SAME MOMENTIVE PERFORMANCE MAT INC (US) 2016-10-05 EP disclosed
US-20160243264-A1 Imaging Beta-Amyloid Peptides Aggregation HONG KONG BAPTIST UNIVERSITY (HK) 2016-08-25 US disclosed
EP-2137198-B1 EPOXYSILANES, PROCESSES FOR THEIR MANUFACTURE AND CURABLE COMPOSITIONS CONTAINING SAME MOMENTIVE PERFORMANCE MAT INC (US) 2016-05-18 EP disclosed
EP-2160424-B1 CURABLE SILYL-CONTAINING POLYMER COMPOSITION CONTAINING PAINT ADHESION ADDITIVE MOMENTIVE PERFORMANCE MAT INC (US) 2015-03-04 EP disclosed
US-8747804-B2 Modified zinc oxide particles BASF SE (DE) 2014-06-10 US disclosed
US-8088940-B2 Having an organofunctional group bonded to a silicon atom through a stable bridging group that is able to react with an organic resin (2,2,4,4,6-pentamethyl-[1,3,2]dioxasilinane); enhanced storage stability, adhesion strength, durability, filler dispersibility, tensile strength, elongation, tear strength MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-01-03 US disclosed
US-7989651-B2 trimethoxysilylpropyl-carbamic acid oxiranylmethyl ester; reacting glycidol with gamma-isocyanatopropyltriethoxysilane in presence of dibutyltin laurate catalyst MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2011-08-02 US disclosed
US-20110130273-A1 MODIFIED ZINC OXIDE PARTICLES BASF SE (DE) 2011-06-02 US disclosed
US-20100184887-A1 HYBRID NANOPARTICLES BASF SE (DE) 2010-07-22 US disclosed
EP-2142558-A1 HYDROLYZABLE SILANES OF LOW VOC-GENERATING POTENTIAL AND RESINOUS COMPOSITIONS CONTAINING SAME Momentive Performance Materials Inc. (US) 2010-01-13 EP disclosed
EP-2137198-A1 EPOXYSILANES, PROCESSES FOR THEIR MANUFACTURE AND CURABLE COMPOSITIONS CONTAINING SAME Momentive Performance Materials Inc. (US) 2009-12-30 EP disclosed
US-7569645-B2 Curable silyl-containing polymer composition containing paint adhesion additive MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2009-08-04 US disclosed
WO-2009005642-A1 CURABLE SILYL-CONTAINING POLYMER COMPOSITION CONTAINING PAINT ADHESION ADDITIVE MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2009-01-08 WO disclosed
US-20090005498-A1 Curable silyl-containing polymer composition containing paint adhesion additive MOMENTIVE PERFORMANCE MATERIALS INC. 2009-01-01 US disclosed
WO-2008121360-A1 HYDROLYZABLE SILANES OF LOW VOC-GENERATING POTENTIAL AND RESINOUS COMPOSITIONS CONTAINING SAME MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-10-09 WO disclosed
US-20080237537-A1 Hydrolyzable silanes of low VOC-generating potential and resinous compositions containing same MOMENTIVE PERFORMANCE MATERIALS INC. 2008-10-02 US disclosed
WO-2008112150-A1 EPOXYSILANES, PROCESSES FOR THEIR MANUFACTURE AND CURABLE COMPOSITIONS CONTAINING SAME MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-09-18 WO disclosed
US-20080221238-A1 Epoxysilanes, processes for their manufacture and curable compositions containing same MOMENTIVE PERFORMANCE MATERIALS INC. 2008-09-11 US disclosed
US-7390628-B2 Microparticle-based diagnostic methods UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2008-06-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110130273-A1 MODIFIED ZINC OXIDE PARTICLES SOD1, LPO, SOD3 EPHX1 3226/4885LMNA 3595/4885
US-20080237537-A1 Hydrolyzable silanes of low VOC-generating potential and resinous compositions containing same GSTM1, GSTP1, GSTM2 EPHX1 148/4885LMNA 3705/4885
US-20100184887-A1 HYBRID NANOPARTICLES RAB5IF, TTPA, PRNP EPHX1 3044/4885LMNA 398/4885
US-20160243264-A1 Imaging Beta-Amyloid Peptides Aggregation APP, IAPP, APBA1 EPHX1 3826/4885LMNA 1196/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.