Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOS | P01100 | 1/20 | 0.63 |
| ▸ | TTR | P02766 | 1/20 | 0.63 |
| ▸ | JUN | P05412 | 1/20 | 0.63 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.63 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.63 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | MMP1 | P03956 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | LDHA | P00338 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.50 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL934771 | 0.96 | FOS (0.58) | FOSTTRJUNNR3C1HSD17B1 | |
| SCHEMBL935389 | 0.94 | HSD17B2 (0.56) | FOSTTRJUNNR3C1HSD17B1 | |
| SCHEMBL934471 | 0.87 | FOS (0.64) | FOSTTRJUNNR3C1HSD17B1 | |
| SCHEMBL20162271 | 0.86 | FOS (0.46) | FOSTTRJUNNR3C1HSD17B1 | |
| SCHEMBL933400 | 0.84 | FOS (0.61) | FOSTTRJUNNR3C1HSD17B1 | |
| SCHEMBL490769 | 0.84 | HSD17B2 (0.60) | FOSTTRJUNNR3C1HSD17B1 | |
| SCHEMBL20162275 | 0.84 | FOS (0.43) | FOSTTRJUNNR3C1HSD17B1 | |
| SCHEMBL20162267 | 0.84 | LDHA (0.46) | FOSTTRJUNNR3C1HSD17B1 | |
| SCHEMBL491190 | 0.83 | LDHA (0.76) | FOSTTRJUNNR3C1HSD17B1 | |
| SCHEMBL934658 | 0.82 | FOS (0.58) | FOSTTRJUNNR3C1HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180207080-A1 | COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS | MERCK PATENT GMBH (DE) | 2018-07-26 | — | — | US | claimed |
| EP-3322400-A1 | COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS | Merck Patent GmbH (DE) | 2018-05-23 | — | — | EP | claimed |
| WO-2017008877-A1 | COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS | MERCK PATENT GMBH (DE) | 2017-01-19 | — | — | WO | claimed |
| WO-2011006566-A2 | MONOMETHOXY-HYDROXY-BENZYLMALONATES | MERCK PATENT GMBH (DE) | 2011-01-20 | — | — | WO | claimed |
| US-20180207080-A1 | COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS | MERCK PATENT GMBH (DE) | 2018-07-26 | — | — | US | disclosed |
| EP-3322400-A1 | COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS | Merck Patent GmbH (DE) | 2018-05-23 | — | — | EP | disclosed |
| WO-2017008877-A1 | COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS | MERCK PATENT GMBH (DE) | 2017-01-19 | — | — | WO | disclosed |
| EP-2931714-B1 | SUBSTITUTED QUINONES OR ANALOGUES AS COLOURING AGENTS | MERCK PATENT GMBH (DE) | 2016-12-21 | — | — | EP | disclosed |
| US-9458142-B2 | Substituted quinones or analogues as colouring agents | MERCK PATENT GMBH (DE) | 2016-10-04 | — | — | US | disclosed |
| WO-2016142026-A1 | FLUORINE SURFACTANTS IN EMULSIONS | MERCK PATENT GMBH (DE) | 2016-09-15 | — | — | WO | disclosed |
| US-20150315177-A1 | SUBSTITUTED QUINONES OR ANALOGUES AS COLOURING AGENTS | MERCK PATENT GMBH (DE) | 2015-11-05 | — | — | US | disclosed |
| EP-2931714-A1 | SUBSTITUTED QUINONES OR ANALOGUES AS COLOURING AGENTS | Merck Patent GmbH (DE) | 2015-10-21 | — | — | EP | disclosed |
| US-20130059924-A1 | PHOTOSTABILISERS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-03-07 | — | — | US | disclosed |
| US-20130058879-A1 | TRIAZINES AS REACTION ACCELERATORS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-03-07 | — | — | US | disclosed |
| WO-2012107158-A1 | 1,3-DIOXAN-5-ONE COMPOUNDS | MERCK PATENT GMBH (DE) | 2012-08-16 | — | — | WO | disclosed |
| WO-2012065685-A1 | ASCORBIC ACID DERIVATIVES AS OXIDATION DYE COMPONENTS | MERCK PATENT GMBH (DE) | 2012-05-24 | — | — | WO | disclosed |
| WO-2012028245-A1 | DYE-ASCORBIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2012-03-08 | — | — | WO | disclosed |
| WO-2011141111-A2 | TRIAZINES AS REACTION ACCELERATORS | MERCK PATENT GMBH (DE) | 2011-11-17 | — | — | WO | disclosed |
| WO-2011141110-A2 | PHOTO-STABILIZING AGENTS | MERCK PATENT GMBH (DE) | 2011-11-17 | — | — | WO | disclosed |
| WO-2011006566-A2 | MONOMETHOXY-HYDROXY-BENZYLMALONATES | MERCK PATENT GMBH (DE) | 2011-01-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150315177-A1 | SUBSTITUTED QUINONES OR ANALOGUES AS COLOURING AGENTS | KRT18, IK, SDHA | FOS 3894/4885TTR 301/4885JUN 3501/4885 |
| US-20180207080-A1 | COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS | LPO, CAT, GPX4 | FOS 43/4885TTR 682/4885JUN 756/4885 |
| US-20130059924-A1 | PHOTOSTABILISERS | ALDH1A1, ALDH18A1, ALDH1A2 | FOS 1418/4885TTR 498/4885JUN 2929/4885 |
| US-20130058879-A1 | TRIAZINES AS REACTION ACCELERATORS | TYR, NAT1, TERT | FOS 3952/4885TTR 428/4885JUN 1344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.