SCHEMBL20164346

SCHEMBL20164346

CCNc1nc(NC)c2nc(NCC(O)CC)nc(NC)c2n1

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC29A1 Q99808 1/20 0.36
LMNA P02545 3/20 0.34
GAA P10253 4/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
MCL1 Q07820 1/20 0.33
ATG4B Q9Y4P1 1/20 0.32
CYP1A2 P05177 2/20 0.31
CYP2C19 P33261 2/20 0.31
HTT P42858 2/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
KDM4E B2RXH2 1/20 0.30
GLA P06280 1/20 0.30
APP P05067 1/20 0.30
BCHE P06276 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL20164312 0.98 SLC29A1 (0.35) SLC29A1LMNAGAAL3MBTL1MEN1
SCHEMBL20179367 0.88 SLC29A1 (0.43) SLC29A1LMNAMEN1KMT2AATG4B
SCHEMBL20164506 0.88 SLC29A1 (0.43) SLC29A1LMNAMEN1KMT2AATG4B
Hydrochloric Acid SCHEMBL20164415 0.87 SLC29A1 (0.42) SLC29A1LMNAMEN1KMT2AATG4B
SCHEMBL20164425 0.87 YTHDC1 (0.38) SLC29A1LMNAGAAATG4BSMN1; SMN2
SCHEMBL30560032 0.83 CDK2 (0.38) SLC29A1KDM4E
SCHEMBL20164687 0.83 CDK2 (0.38) SLC29A1KDM4E
SCHEMBL16094592 0.83 LMNA (0.46) SLC29A1LMNAGAAL3MBTL1MEN1
SCHEMBL20179362 0.83 LMNA (0.35) SLC29A1LMNAGAAL3MBTL1CYP1A2
Hydrochloric Acid SCHEMBL20164747 0.82 CDK2 (0.38) SLC29A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180141953-A1 Novel Breathing Control Modulating Compounds, and Methods of Making and Using Same NEURAD LTD. (IL) 2018-05-24 US claimed
US-20250057848-A1 GAL475 COMPOSITIONS AND METHODS OF USE THEREOF NEURIM PHARMACEUTICALS (1991) LTD. (IL) 2025-02-20 US disclosed
EP-3316890-B1 NOVEL BREATHING CONTROL MODULATING COMPOUNDS, AND METHODS OF MAKING AND USING SAME NEURAD LTD (IL) 2023-09-06 EP disclosed
EP-3316890-B1 NOVEL BREATHING CONTROL MODULATING COMPOUNDS, AND METHODS OF MAKING AND USING SAME NEURAD LTD (IL) 2023-09-06 EP disclosed
US-10294228-B2 Breathing control modulating compounds, and methods of making and using same NEURAD LTD. (IL) 2019-05-21 US disclosed
US-20180141953-A1 Novel Breathing Control Modulating Compounds, and Methods of Making and Using Same NEURAD LTD. (IL) 2018-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180141953-A1 Novel Breathing Control Modulating Compounds, and Methods of Making and Using Same MTNR1B, CHRM3, PER2 SLC29A1 4472/4885LMNA 1394/4885GAA 1936/4885
US-20250057848-A1 GAL475 COMPOSITIONS AND METHODS OF USE THEREOF GPR119, GPR35, GPR55 SLC29A1 2077/4885LMNA 2585/4885GAA 1082/4885
US-10294228-B2 Breathing control modulating compounds, and methods of making and using same MTNR1B, PDE3A, CHRM3 SLC29A1 4518/4885LMNA 1200/4885GAA 1576/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.