Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 7/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20170684 | 0.86 | MTNR1A (0.34) | MTNR1AMTNR1BNPSR1 | |
| SCHEMBL20170672 | 0.85 | OPRD1 (0.37) | MTNR1AMTNR1BLMNACYP2C9TUBB1 | |
| SCHEMBL20170753 | 0.82 | GABRA1 (0.39) | MTNR1AMTNR1BNQO2LMNAKDM4E | |
| SCHEMBL20170738 | 0.82 | HTR1A (0.40) | MTNR1AMTNR1BNQO2KMT2ACYP1A2 | |
| SCHEMBL20170652 | 0.80 | OPRM1 (0.37) | MTNR1AMTNR1BNQO2HCRTR1 | |
| SCHEMBL20170607 | 0.80 | OPRM1 (0.37) | MTNR1AMTNR1BNQO2HCRTR1 | |
| SCHEMBL20170728 | 0.80 | OPRM1 (0.37) | MTNR1AMTNR1BNQO2HCRTR1 | |
| SCHEMBL20170612 | 0.78 | ADRA1A (0.35) | — | |
| SCHEMBL20170605 | 0.78 | ADRA1A (0.35) | — | |
| SCHEMBL20170645 | 0.72 | OPRM1 (0.39) | MTNR1AMTNR1BNQO2LMNATUBB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2453895-B1 | (+) - MORPHINANS AS ANTAGONISTS OF TOLL-LIKE RECEPTOR 9 AND THERAPEUTIC USES THEREOF | MALLINCKRODT LLC (US) | 2018-05-23 | — | — | EP | disclosed |