SCHEMBL20173738

SCHEMBL20173738

CN1c2ccccc2Oc2ccc(-c3ccc4c(c3)N(C)c3ccccc3S4)cc21

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.56
NOX1 Q9Y5S8 5/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
LMNA P02545 1/20 0.50
MAPT P10636 1/20 0.50
MAPK1 P28482 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
MEN1 O00255 1/20 0.48
ADRA2A P08913 1/20 0.48
ADRA2B P18089 1/20 0.48
ADRA2C P18825 1/20 0.48
CHRM3 P20309 1/20 0.48
SLC6A2 P23975 1/20 0.48
HTR2C P28335 1/20 0.48
SLC6A4 P31645 1/20 0.48
DRD3 P35462 1/20 0.48
HTR2B P41595 1/20 0.48
KMT2A Q03164 1/20 0.48
ALDH1A1 P00352 2/20 0.40
KDM4E B2RXH2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19849740 0.87 MAOA (0.54) MAOANOX1L3MBTL1LMNAMAPT
SCHEMBL16810785 0.83 KDM4E (0.45) L3MBTL1LMNAMAPTMEN1KMT2A
SCHEMBL16810782 0.81 MAOA (0.68) MAOANOX1L3MBTL1LMNAMAPT
SCHEMBL22115454 0.80 NOX1 (0.49) MAOANOX1L3MBTL1LMNAMAPT
SCHEMBL19041843 0.78 BCHE (0.36) MAOANOX1L3MBTL1LMNAMAPT
SCHEMBL16810643 0.77 CA12 (0.40) L3MBTL1MEN1KMT2AALDH1A1KDM4E
SCHEMBL7170967 0.77 MAOA (0.73) MAOANOX1L3MBTL1LMNAMAPT
SCHEMBL18542354 0.77 CA12 (0.40) L3MBTL1MEN1KMT2AALDH1A1KDM4E
SCHEMBL22814800 0.77 SMN1; SMN2 (0.47) LMNAMAPTTDP1MEN1KMT2A
SCHEMBL23954364 0.76 MAOA (0.59) MAOANOX1L3MBTL1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11685859-B2 Organic light emitting device LG CHEM, LTD. (KR) 2023-06-27 US disclosed
US-20220144862-A1 ORGANIC COMPOUND AND APPLICATION THEREOF WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2022-05-12 US disclosed
US-20210296586-A1 THERMALLY ACTIVATED DELAYED FLOURESCENCE (TADF) MATERIAL, SYNTHESIZING METHOD THEREOF, AND ELECTROLUMINESCENT DEVICE Wuhan China Star Optoelectronics Semiconductor Display Technology Ltd. (CN) 2021-09-23 US disclosed
US-20210147442-A1 ORGANIC COMPOUND, ELECTROLUMINESCENT MATERIAL, AND APPLICATION THEREOF WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2021-05-20 US disclosed
US-20210009894-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2021-01-14 US disclosed
US-10822330-B2 Heterocyclic compound and organic light emitting diode containing same LG CHEM, LTD. (KR) 2020-11-03 US disclosed
US-20200343454-A1 LIGHT THERMALLY ACTIVATED DELAYED FLUORESCENCE (TADF) MATERIAL, PREPARING METHOD THEREOF, AND ELECTROLUMINESCENT DEVICE WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (IL) 2020-10-29 US disclosed
US-10781366-B2 Spiro compound and organic light-emitting device comprising same LG CHEM, LTD. (KR) 2020-09-22 US disclosed
US-10651411-B2 Compound and organic light emitting device containing same LG CHEM, LTD. (KR) 2020-05-12 US disclosed
US-20180148639-A1 SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2018-05-31 US disclosed
US-20180145272-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CONTAINING SAME LG CHEM, LTD. (KR) 2018-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210296586-A1 THERMALLY ACTIVATED DELAYED FLOURESCENCE (TADF) MATERIAL, SYNTHESIZING METHOD THEREOF, AND ELECTROLUMINESCENT DEVICE TEAD3, NUTF2, TEAD1 MAOA 607/4885NOX1 2228/4885L3MBTL1 3047/4885
US-20210147442-A1 ORGANIC COMPOUND, ELECTROLUMINESCENT MATERIAL, AND APPLICATION THEREOF ILK, OSTC, LEF1 MAOA 1429/4885NOX1 683/4885L3MBTL1 1968/4885
US-20220144862-A1 ORGANIC COMPOUND AND APPLICATION THEREOF TEAD2, TEAD1, TEAD4 MAOA 1258/4885NOX1 1212/4885L3MBTL1 1145/4885
US-20180145272-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CONTAINING SAME CRY1, CRY2, OR10J3 MAOA 851/4885NOX1 415/4885L3MBTL1 349/4885
US-10781366-B2 Spiro compound and organic light-emitting device comprising same CRY1, NR2E3, ERG MAOA 3325/4885NOX1 1161/4885L3MBTL1 2838/4885
US-20180148639-A1 SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME CRY1, NR2E3, ERG MAOA 3325/4885NOX1 1161/4885L3MBTL1 2838/4885
US-20200343454-A1 LIGHT THERMALLY ACTIVATED DELAYED FLUORESCENCE (TADF) MATERIAL, PREPARING METHOD THEREOF, AND ELECTROLUMINESCENT DEVICE ADGRF1, ADORA1, HTR1F MAOA 266/4885NOX1 3965/4885L3MBTL1 3782/4885
US-10651411-B2 Compound and organic light emitting device containing same CRY1, CRY2, OR10J3 MAOA 851/4885NOX1 415/4885L3MBTL1 349/4885
US-10822330-B2 Heterocyclic compound and organic light emitting diode containing same CRY1, CRY2, PER2 MAOA 385/4885NOX1 178/4885L3MBTL1 895/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.