Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.51 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.50 |
| ▸ | METAP2 | P50579 | 1/20 | 0.50 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.50 |
| ▸ | AXL | P30530 | 1/20 | 0.47 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.46 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.46 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23843626 | 0.92 | CYP19A1 (0.60) | CYP2A6ALDH1A1CYP1A2CYP3A4HSP90AA1 | |
| SCHEMBL3194702 | 0.86 | CYP2A6 (0.74) | CYP2A6ALDH1A1CYP1A2CYP3A4HSP90AA1 | |
| SCHEMBL2732828 | 0.83 | CYP2C9 (0.50) | CYP2A6ALDH1A1CYP1A2CYP3A4CYP19A1 | |
| SCHEMBL19556523 | 0.81 | CYP2A6 (0.52) | CYP2A6ALDH1A1CYP1A2CYP3A4HSP90AA1 | |
| SCHEMBL18905222 | 0.80 | CYP19A1 (0.69) | CYP2A6ALDH1A1CYP1A2CYP3A4HSP90AA1 | |
| SCHEMBL12925581 | 0.80 | CYP2A6 (0.67) | CYP2A6ALDH1A1CYP1A2CYP3A4HSP90AA1 | |
| SCHEMBL2462787 | 0.80 | CHRNB2 (0.69) | ALDH1A1MAPTKDM4ETP53HPGD | |
| SCHEMBL12279610 | 0.80 | USP8 (0.47) | CYP2A6ALDH1A1CYP1A2CYP3A4CYP19A1 | |
| SCHEMBL2225949 | 0.78 | HPGDS (0.53) | CYP2A6ALDH1A1CYP19A1AXLPBRM1 | |
| SCHEMBL10031168 | 0.78 | CYP2A6 (0.65) | CYP2A6ALDH1A1CYP1A2CYP3A4HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10892423-B2 | Condensed cyclic compound and organic light-emitting device including the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2021-01-12 | — | — | US | disclosed |
| US-10038146-B2 | Organic light-emitting compound and organic electroluminescent device using same | DOOSAN CORPORATION (KR) | 2018-07-31 | — | — | US | disclosed |
| US-10038146-B2 | Organic light-emitting compound and organic electroluminescent device using same | DOOSAN CORPORATION (KR) | 2018-07-31 | — | — | US | disclosed |
| US-20180159050-A1 | CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2018-06-07 | — | — | US | disclosed |
| US-9761813-B2 | Organic light-emitting compound and organic electroluminescent device using same | DOOSAN CORPORATION (KR) | 2017-09-12 | — | — | US | disclosed |
| US-9761813-B2 | Organic light-emitting compound and organic electroluminescent device using same | DOOSAN CORPORATION (KR) | 2017-09-12 | — | — | US | disclosed |
| US-9761813-B2 | Organic light-emitting compound and organic electroluminescent device using same | DOOSAN CORPORATION (KR) | 2017-09-12 | — | — | US | disclosed |
| CN-104379572-B | Benzo [a] carbazole compound, electron transport materials and use its organic electric-field light-emitting element | 捷恩智株式会社 | 2016-09-21 | — | — | CN | disclosed |
| WO-2015111943-A1 | ORGANIC COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE CONTAINING SAME | 주식회사 두산 | 2015-07-30 | — | — | WO | disclosed |
| WO-2015111943-A1 | ORGANIC COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE CONTAINING SAME | 주식회사 두산 | 2015-07-30 | — | — | WO | disclosed |
| US-7030128-B2 | Central nervous system disorders; anxiolytic agents; anticonvulsants; cognition activators; side effect reduction | MERCK SHARP & DOHME LTD. (GB) | 2006-04-18 | — | — | US | disclosed |
| US-20060014742-A1 | Amide derivative | NIPPON SHINYAKU CO., LTD. (JP) | 2006-01-19 | — | — | US | disclosed |
| CN-1678590-A | Amide derivative and pharmaceutical | NIPPON SHINYAKU CO LTD (JP) | 2005-10-05 | — | — | CN | disclosed |
| EP-1533304-A1 | AMIDE DERIVATIVE | Nippon Shinyaku Co., Ltd. (JP) | 2005-05-25 | — | — | EP | disclosed |
| US-20050004125-A1 | Heteroaryl amines as glycogen synthase kinase 3beta inhibitors (gsk3 inhibitors) | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-01-06 | — | — | US | disclosed |
| EP-1448556-A1 | HETEROARYL AMINES AS GLYCOGEN SYNTHASE KINASE 3BETA INHIBITORS (GSK3 INHIBITORS) | JANSSEN PHARMACEUTICA N.V. (BE) | 2004-08-25 | — | — | EP | disclosed |
| US-20040092533-A1 | Imidazo-pyrimidine derivatives as ligands for gaba receptors | MERCK SHARP & DOHME LTD. (GB) | 2004-05-13 | — | — | US | disclosed |
| EP-1383768-A1 | IMIDAZO-PYRIMIDINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS | MERCK SHARP & DOHME LTD. (GB) | 2004-01-28 | — | — | EP | disclosed |
| WO-2003037891-A1 | HETEROARYL AMINES AS GLYCOGEN SYNTHASE KINASE 3BETA INHIBITORS (GSK3 INHIBITORS) | JANSSEN PHARMACEUTICA N.V. (BE) | 2003-05-08 | — | — | WO | disclosed |
| WO-2002076983-A1 | IMIDAZO-PYRIMIDINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS | MERCK SHARP & DOHME LIMITED (GB) | 2002-10-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10038146-B2 | Organic light-emitting compound and organic electroluminescent device using same | IDO1, IDO2, KYNU | CYP2A6 2126/4885ALDH1A1 458/4885CYP1A2 737/4885 |
| US-20060014742-A1 | Amide derivative | ABL1, ABL2, BCR | CYP2A6 239/4885ALDH1A1 753/4885CYP1A2 252/4885 |
| US-20040092533-A1 | Imidazo-pyrimidine derivatives as ligands for gaba receptors | GABRA3, GABRA1, GABRA4 | CYP2A6 425/4885ALDH1A1 495/4885CYP1A2 594/4885 |
| US-20180159050-A1 | CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | CRY1, CCNE2, CCNT1 | CYP2A6 3284/4885ALDH1A1 127/4885CYP1A2 1512/4885 |
| US-10892423-B2 | Condensed cyclic compound and organic light-emitting device including the same | CRY1, CCNE2, CCNT1 | CYP2A6 3284/4885ALDH1A1 127/4885CYP1A2 1512/4885 |
| US-20050004125-A1 | Heteroaryl amines as glycogen synthase kinase 3beta inhibitors (gsk3 inhibitors) | GSK3B, GSK3A, GSKIP | CYP2A6 1915/4885ALDH1A1 3842/4885CYP1A2 1024/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.