Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2015355 | 1.00 | CYP4F2 (0.40) | CYP4F2CYP4A11ALDH1A1TRPA1MEN1 | |
| SCHEMBL18978425 | 0.84 | PKM (0.39) | CYP4F2CYP4A11MEN1KMT2APKM | |
| SCHEMBL22446274 | 0.84 | PKM (0.39) | CYP4F2CYP4A11MEN1KMT2APKM | |
| SCHEMBL28072693 | 0.82 | CYP4F2 (0.39) | CYP4F2CYP4A11ALDH1A1TRPA1MEN1 | |
| Hydrochloric Acid SCHEMBL18954073 | 0.82 | PKM (0.38) | CYP4F2CYP4A11MEN1KMT2APKM | |
| Hydrochloric Acid SCHEMBL28224630 | 0.82 | PKM (0.38) | CYP4F2CYP4A11MEN1KMT2APKM | |
| SCHEMBL19989708 | 0.81 | DGAT1 (0.33) | — | |
| SCHEMBL12985153 | 0.81 | PKM (0.38) | CYP4F2CYP4A11ALDH1A1TRPA1MEN1 | |
| SCHEMBL17830429 | 0.81 | PKM (0.38) | CYP4F2CYP4A11ALDH1A1TRPA1MEN1 | |
| SCHEMBL15764440 | 0.80 | CYP4F2 (0.36) | CYP4F2CYP4A11ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11981696-B2 | Fluoro-pyridinone phosphates and boronates useful as antibacterial agents | PFIZER INC. (US) | 2024-05-14 | — | — | US | disclosed |
| US-20210053926-A1 | SUBSTITUTED BENZAZINONES AS ANTIBACTERIAL COMPOUNDS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2021-02-25 | — | — | US | disclosed |
| US-20210053926-A1 | SUBSTITUTED BENZAZINONES AS ANTIBACTERIAL COMPOUNDS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2021-02-25 | — | — | US | disclosed |
| US-10781184-B2 | Substituted benzazinones as antibacterial compounds | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2020-09-22 | — | — | US | disclosed |
| US-10781184-B2 | Substituted benzazinones as antibacterial compounds | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2020-09-22 | — | — | US | disclosed |
| WO-2019175828-A1 | FLUORO-PYRIDINONE PHOSPHATES AND BORONATES USEFUL AS ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 2019-09-19 | — | — | WO | disclosed |
| CN-105829288-B | Antibacterial 1H- indazole and 1H- indole derivatives | 爱杜西亚药品有限公司 | 2019-01-15 | — | — | CN | disclosed |
| US-20180362474-A1 | SUBSTITUTED BENZAZINONES AS ANTIBACTERIAL COMPOUNDS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2018-12-20 | — | — | US | disclosed |
| EP-3386950-A1 | SUBSTITUTED BENZAZINONES AS ANTIBACTERIAL COMPOUNDS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2018-10-17 | — | — | EP | disclosed |
| CN-108368053-A | Substituted benzazepine derivatives as antibacterial compounds | 葛兰素史密斯克莱知识产权发展有限公司 | 2018-08-03 | — | — | CN | disclosed |
| US-8809333-B2 | Imidazole, pyrazole, and triazole derivatives useful as antibacterial agents | PFIZER INC. (US) | 2014-08-19 | — | — | US | disclosed |
| US-8809333-B2 | Imidazole, pyrazole, and triazole derivatives useful as antibacterial agents | PFIZER INC. (US) | 2014-08-19 | — | — | US | disclosed |
| US-8779148-B2 | Fluoro-pyridinone derivatives useful as antibacterial agents | PFIZER INC. (US) | 2014-07-15 | — | — | US | disclosed |
| US-20140057919-A1 | FLUORO-PYRIDINONE DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 2014-02-27 | — | — | US | disclosed |
| US-20140038975-A1 | Imidazole, Pyrazole, and Triazole Derivatives Useful As Antibacterial Agents | BROWN MATTHEW FRANK (US) | 2014-02-06 | — | — | US | disclosed |
| US-20140038975-A1 | Imidazole, Pyrazole, and Triazole Derivatives Useful As Antibacterial Agents | BROWN MATTHEW FRANK (US) | 2014-02-06 | — | — | US | disclosed |
| US-8624034-B2 | Fluoro-pyridinone derivatives useful as antibacterial agents | PFIZER INC. (US) | 2014-01-07 | — | — | US | disclosed |
| WO-2012137099-A1 | IMIDAZOLE, PYRAZOLE, AND TRIAZOLE DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 2012-10-11 | — | — | WO | disclosed |
| US-20120232083-A1 | FLUORO-PYRIDINONE DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | PFIZER INC | 2012-09-13 | — | — | US | disclosed |
| WO-2011073845-A1 | N-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 2011-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210053926-A1 | SUBSTITUTED BENZAZINONES AS ANTIBACTERIAL COMPOUNDS | LPXN, MLX, ZYX | CYP4F2 1569/4885CYP4A11 3429/4885ALDH1A1 2221/4885 |
| US-20180362474-A1 | SUBSTITUTED BENZAZINONES AS ANTIBACTERIAL COMPOUNDS | LPXN, MLX, ZYX | CYP4F2 1569/4885CYP4A11 3429/4885ALDH1A1 2221/4885 |
| US-20140038975-A1 | Imidazole, Pyrazole, and Triazole Derivatives Useful As Antibacterial Agents | AADAC, TPX2, NLRP3 | CYP4F2 2034/4885CYP4A11 3774/4885ALDH1A1 2967/4885 |
| US-10781184-B2 | Substituted benzazinones as antibacterial compounds | LPXN, MLX, ZYX | CYP4F2 1569/4885CYP4A11 3429/4885ALDH1A1 2221/4885 |
| US-20120232083-A1 | FLUORO-PYRIDINONE DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | PRDX1, PRXL2A, PRDX4 | CYP4F2 612/4885CYP4A11 4235/4885ALDH1A1 2047/4885 |
| US-11981696-B2 | Fluoro-pyridinone phosphates and boronates useful as antibacterial agents | BPGM, MLX, PRXL2A | CYP4F2 625/4885CYP4A11 4471/4885ALDH1A1 3619/4885 |
| US-20140057919-A1 | FLUORO-PYRIDINONE DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | PRDX1, PRXL2A, PRDX4 | CYP4F2 612/4885CYP4A11 4235/4885ALDH1A1 2047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.