Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MPI | P34949 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2017442 | 0.88 | SLC40A1 (0.44) | SLC40A1L3MBTL1KDM4EMPIMEN1 | |
| SCHEMBL2014289 | 0.85 | KDM4E (0.36) | SLC40A1L3MBTL1KDM4EMPIMEN1 | |
| SCHEMBL2014290 | 0.85 | KDM4E (0.36) | SLC40A1L3MBTL1KDM4EMPIMEN1 | |
| SCHEMBL2013352 | 0.82 | METAP2 (0.43) | SLC40A1L3MBTL1KDM4EMPIMEN1 | |
| SCHEMBL2017535 | 0.81 | MAPT (0.41) | L3MBTL1KDM4EMPIALDH1A1MAPT | |
| SCHEMBL2013524 | 0.80 | HTR1A (0.42) | L3MBTL1KDM4EALDH1A1LMNAFFAR4 | |
| SCHEMBL2163892 | 0.79 | L3MBTL1 (0.44) | SLC40A1PRKDCL3MBTL1KDM4EMPI | |
| SCHEMBL2018198 | 0.78 | METAP2 (0.41) | SLC40A1L3MBTL1KDM4EMPIMEN1 | |
| SCHEMBL2014288 | 0.76 | L3MBTL1 (0.41) | SLC40A1L3MBTL1KDM4EMPIMEN1 | |
| SCHEMBL2013917 | 0.75 | METAP2 (0.43) | L3MBTL1KDM4EMPIMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011075630-A1 | SUBSTITUTED FUSED ARYL AND HETEROARYL DERIVATIVES AS PI3K INHIBITORS | INCYTE CORPORATION (US) | 2011-06-23 | — | — | WO | disclosed |