Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 6/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 7/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 7/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 4/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20195282 | 0.84 | PPARA (0.33) | PPARACYP4F2CYP4A11CA2KDM4E | |
| SCHEMBL20195263 | 0.79 | L3MBTL1 (0.36) | PPARACYP4F2CYP4A11CA2PPARG | |
| SCHEMBL23309376 | 0.78 | PPARA (0.44) | PPARACYP4F2CYP4A11PPARG | |
| SCHEMBL3229511 | 0.78 | NNMT (0.44) | CYP4F2CYP4A11KDM4EMAPT | |
| SCHEMBL20195249 | 0.76 | MAPT (0.50) | CYP4F2CYP4A11CA2FFAR1KDM4E | |
| SCHEMBL20195262 | 0.75 | CA2 (0.32) | CA2 | |
| SCHEMBL20195254 | 0.73 | ACACB (0.42) | PPARACYP4F2CYP4A11PPARGKDM4E | |
| SCHEMBL20195258 | 0.73 | ACACB (0.47) | CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL2938892 | 0.73 | PPARG (0.39) | PPARACYP4F2CYP4A11PPARGKDM4E | |
| SCHEMBL30942648 | 0.73 | CA2 (0.38) | CYP4F2CYP4A11CA2FFAR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2729447-B1 | POSITIVE ALLOSTERIC MODULATORS OF NICOTINIC ACETYLCHOLINE RECEPTOR | H LUNDBECK AS (DK) | 2018-05-30 | — | — | EP | disclosed |