Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3039623 | 0.90 | S100A4 (0.46) | KIF18APTGS2PTGS1KDM4ELMNA | |
| SCHEMBL5161585 | 0.86 | PTGS2 (0.54) | KIF18AALDH1A1CYP3A4MAPK1PTGS2 | |
| SCHEMBL11224124 | 0.84 | MEN1 (0.61) | KIF18AALDH1A1CYP3A4MAPK1PTGS2 | |
| SCHEMBL7871346 | 0.83 | PTGS2 (0.56) | KIF18AALDH1A1CYP3A4MAPK1PTGS2 | |
| SCHEMBL10977080 | 0.82 | S100A4 (0.45) | KIF18AALDH1A1CYP3A4MAPK1PTGS2 | |
| SCHEMBL9473123 | 0.80 | HTR6 (0.53) | KIF18AALDH1A1CYP3A4MAPK1APP | |
| SCHEMBL9840644 | 0.80 | KIF18A (0.51) | KIF18AALDH1A1CYP3A4MAPK1PTGS2 | |
| SCHEMBL8178017 | 0.79 | PTGDR2 (0.46) | KIF18AKDM4EKMT2A | |
| SCHEMBL7584026 | 0.79 | PTGS2 (0.50) | PTGS2PTGS1KMT2A | |
| SCHEMBL7643603 | 0.79 | PTGS2 (0.54) | KIF18AALDH1A1CYP3A4MAPK1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011075942-A1 | METHOD FOR PREPARING POLY (DIPHENYL ETHER SULFONE) AND POLY (DIPHENYL ETHER DIPHENYL SULFONE) TERNARY POLYMER | 金发科技股份有限公司 (CN) | 2011-06-30 | — | — | WO | disclosed |