Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | IDH1 | O75874 | 2/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | VNN1 | O95497 | 1/20 | 0.44 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.44 |
| ▸ | UBA2 | Q9UBT2 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 3/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8093804 | 0.84 | TAAR1 (0.56) | IDH1LTA4HSAE1UBA2IDO1 | |
| SCHEMBL8992963 | 0.82 | LTA4H (0.46) | KDM4ELTA4HSAE1UBA2IDO1 | |
| SCHEMBL8085716 | 0.81 | CALM1 (0.55) | IDH1LTA4HSAE1UBA2IDO1 | |
| SCHEMBL14346503 | 0.81 | CYP2A6 (0.73) | LOXL2CYP11B1CYP11B2CYP2A6ALDH1A1 | |
| SCHEMBL11087087 | 0.81 | LTA4H (0.53) | IDH1LTA4HSAE1UBA2IDO1 | |
| M-Xylene SCHEMBL28366327 | 0.80 | CYP2A6 (0.64) | LOXL2CYP11B1CYP11B2CYP2A6ALDH1A1 | |
| SCHEMBL29459538 | 0.80 | TAAR1 (0.60) | ALDH1A1LTA4HIDO1TAAR1ACHE | |
| SCHEMBL30000562 | 0.80 | TAAR1 (0.60) | ALDH1A1LTA4HIDO1TAAR1ACHE | |
| SCHEMBL1263547 | 0.80 | TAAR1 (0.60) | ALDH1A1LTA4HIDO1TAAR1ACHE | |
| SCHEMBL28862319 | 0.79 | LOXL2 (0.47) | LOXL2CYP2A6SAE1UBA2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10227362-B2 | Anti-pulmonary tuberculosis nitroimidazole derivative | MEDSHINE DISCOVERY INC. (CN) | 2019-03-12 | — | — | US | disclosed |
| US-20180162878-A1 | ANTI-PULMONARY TUBERCULOSIS NITROIMIDAZOLE DERIVATIVE | MEDSHINE DISCOVERY INC. (CN) | 2018-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180162878-A1 | ANTI-PULMONARY TUBERCULOSIS NITROIMIDAZOLE DERIVATIVE | NDUFV1, NDUFV2, MT-ND4 | LOXL2 3321/4885CYP11B1 241/4885CYP11B2 192/4885 |
| US-10227362-B2 | Anti-pulmonary tuberculosis nitroimidazole derivative | NDUFV1, NDUFV2, MT-ND4 | LOXL2 3321/4885CYP11B1 241/4885CYP11B2 192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.