Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INPP5A | Q14642 | 1/20 | 0.36 |
| ▸ | ITPR3 | Q14573 | 4/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.31 |
| ▸ | ITPR2 | Q14571 | 1/20 | 0.30 |
| ▸ | ITPR1 | Q14643 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL252069 | 0.98 | INPP5A (0.37) | INPP5AITPR3SMPD1ITPR2ITPR1 | |
| SCHEMBL6567878 | 0.86 | INPP5A (0.36) | INPP5AITPR3 | |
| SCHEMBL601363 | 0.82 | GAA (0.41) | INPP5AITPR3SMPD1ITPR2ITPR1 | |
| SCHEMBL14165319 | 0.82 | INPP5A (0.37) | INPP5AITPR3SMPD1ITPR2ITPR1 | |
| SCHEMBL29389192 | 0.79 | INPP5A (0.35) | INPP5AITPR3SMPD1 | |
| SCHEMBL14409850 | 0.79 | INPP5A (0.35) | INPP5AITPR3SMPD1 | |
| SCHEMBL5072013 | 0.75 | INPP5A (0.33) | INPP5AITPR3 | |
| SCHEMBL601437 | 0.75 | INPP5A (0.33) | INPP5AITPR3 | |
| SCHEMBL7945649 | 0.74 | INPP5A (0.34) | INPP5A | |
| SCHEMBL10586976 | 0.72 | GAA (0.41) | INPP5AITPR3SMPD1ITPR2ITPR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3065944-B1 | MODIFICATION OF POLYAMIDES | ARKEMA INC (US) | 2022-01-19 | — | — | EP | claimed |
| US-20210361784-A1 | IMAGING AGENTS AND METHODS OF USE | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA | 2021-11-25 | — | — | US | claimed |
| US-10953113-B2 | Imaging agents and methods of use | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2021-03-23 | — | — | US | claimed |
| US-20200078477-A1 | IMAGING AGENTS AND METHODS OF USE | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA | 2020-03-12 | — | — | US | claimed |
| EP-3548021-A1 | IMAGING AGENTS AND METHODS OF USE | The Board of Regents of the University of Oklahoma (US) | 2019-10-09 | — | — | EP | claimed |
| EP-3116951-B1 | TIN-FREE CATALYSTS FOR CROSS-LINKED POLYETHYLENE PIPE AND WIRE | SACO AEI POLYMERS INC (US) | 2019-10-02 | — | — | EP | claimed |
| WO-2018102574-A9 | IMAGING AGENTS AND METHODS OF USE | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2018-08-23 | — | — | WO | claimed |
| WO-2018102574-A1 | IMAGING AGENTS AND METHODS OF USE | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2018-06-07 | — | — | WO | claimed |
| US-9441103-B2 | Tin-free catalysts for cross-linked polyethylene pipe and wire | SACO AEI POLYMERS, INC. (US) | 2016-09-13 | — | — | US | claimed |
| EP-3755675-B1 | ACCELERATED PEROXIDE-CURED RESIN COMPOSITIONS HAVING EXTENDED OPEN TIMES | ARKEMA INC (US) | 2026-05-13 | — | — | EP | disclosed |
| US-12486381-B2 | Accelerated peroxide-cured resin compositions having extended open times | ARKEMA INC. (US) | 2025-12-02 | — | — | US | disclosed |
| US-12458703-B2 | Responsive elastic polymers and methods of making and using same | PURDUE RESEARCH FOUNDATION (US) | 2025-11-04 | — | — | US | disclosed |
| EP-3559153-B1 | EFFICIENT CURATIVE FOR FREE RADICALLY-CROSSLINKABLE POLYMERS | ARKEMA INC (US) | 2025-07-30 | — | — | EP | disclosed |
| CN-119978237-A | Responsive elastomeric polymers and methods of making and using the same | 珀杜研究基金会 | 2025-05-13 | — | — | CN | disclosed |
| WO-2013130297-A1 | MULTIPHOTON CURING METHODS USING NEGATIVE CONTRAST COMPOSITIONS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-09-06 | — | — | WO | disclosed |
| US-20120241158-A1 | RADICAL TRAP IN OIL AND GAS STIMULATION OPERATIONS | ARKEMA INC. (US) | 2012-09-27 | — | — | US | disclosed |
| WO-2011071797-A1 | RADICAL TRAP IN OIL AND GAS STIMULATION OPERATIONS | ARKEMA INC. (US) | 2011-06-16 | — | — | WO | disclosed |
| US-20040241663-A1 | Ligand array processing methods that include a high surface tension fluid deposition step and compositions for practicing the same | AGILENT TECHNOLOGIES, INC. | 2004-12-02 | — | — | US | disclosed |
| US-20040241742-A1 | Ligand array processing methods that include a low surface tension fluid deposition step and compositions for practicing the same | AGILENT TECHNOLOGIES, INC. | 2004-12-02 | — | — | US | disclosed |
| US-20040241880-A1 | Ligand array assays having reduced fluorescent dye degradation and compositions for practicing the same | AGILENT TECHNOLOGIES, INC. | 2004-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12458703-B2 | Responsive elastic polymers and methods of making and using same | CD44, HCAR3, HCAR1 | INPP5A 3595/4885ITPR3 3789/4885SMPD1 2642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.