SCHEMBL2034492

SCHEMBL2034492

COc1ccc(C(=O)c2cc3ccc(OC)cc3oc2=O)cc1

nearest known ligand 0.85

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.85
KDM4E B2RXH2 7/20 0.85
RAB9A P51151 3/20 0.85
NPC1 O15118 2/20 0.85
POLB P06746 1/20 0.85
PKM P14618 2/20 0.83
MEN1 O00255 1/20 0.83
KMT2A Q03164 1/20 0.83
MAOB P27338 5/20 0.72
HPGD P15428 4/20 0.72
GAA P10253 3/20 0.72
SLC16A3 O15427 1/20 0.72
GLA P06280 2/20 0.71
HSD17B10 Q99714 2/20 0.71
LMNA P02545 1/20 0.66
CA12 O43570 1/20 0.64
CA2 P00918 1/20 0.64
CA3 P07451 1/20 0.64
CA4 P22748 1/20 0.64
CA6 P23280 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15662702 0.93 ALDH1A1 (0.79) ALDH1A1KDM4ERAB9ANPC1POLB
SCHEMBL11219544 0.92 ALDH1A1 (0.81) ALDH1A1KDM4ERAB9ANPC1POLB
SCHEMBL51978 0.92 ALDH1A1 (1.00) ALDH1A1KDM4ERAB9ANPC1POLB
SCHEMBL52650 0.91 ALDH1A1 (0.81) ALDH1A1KDM4ERAB9ANPC1POLB
SCHEMBL11219548 0.91 ALDH1A1 (0.76) ALDH1A1KDM4ERAB9ANPC1POLB
SCHEMBL28015513 0.91 MEN1 (1.00) ALDH1A1KDM4ERAB9ANPC1POLB
SCHEMBL11096762 0.90 ALDH1A1 (0.79) ALDH1A1KDM4ERAB9ANPC1POLB
SCHEMBL2996332 0.90 ALDH1A1 (0.74) ALDH1A1KDM4ERAB9ANPC1POLB
SCHEMBL15661472 0.90 ALDH1A1 (0.74) ALDH1A1KDM4ERAB9ANPC1POLB
SCHEMBL6687156 0.90 ALDH1A1 (0.77) ALDH1A1KDM4ERAB9ANPC1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 221 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0022188-A2 Co-initiator compositions for photopolymerization containing 3-acyl-substituted coumarins, photopolymerizable composition and photographic element EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1981-01-14 EP claimed
US-4147552-A Light-sensitive compositions with 3-substituted coumarin compounds as spectral sensitizers EASTMAN KODAK COMPANY (US) 1979-04-03 US claimed
US-12622847-B2 Organosilicon compound and dental composition containing same KURARAY NORITAKE DENTAL INC. (JP) 2026-05-12 US disclosed
EP-4736835-A1 DENTAL POLYMERIZABLE COMPOSITION Kuraray Noritake Dental Inc. (JP) 2026-05-06 EP disclosed
US-12564543-B2 Dental composition KURARAY NORITAKE DENTAL INC. (JP) 2026-03-03 US disclosed
US-12527725-B2 Solvent-free dental adhesive composition KURARAY NORITAKE DENTAL INC. (JP) 2026-01-20 US disclosed
EP-4649938-A1 DENTAL COMPOSITION Kuraray Noritake Dental Inc. (JP) 2025-11-19 EP disclosed
US-12465559-B2 Fluorescent curable dental composition and cured product thereof KURARAY NORITAKE DENTAL INC. (JP) 2025-11-11 US disclosed
US-20250213434-A1 DENTAL CURABLE COMPOSITION HAVING FAVORABLE COLOR COMPATIBILITY KURARAY NORITAKE DENTAL INC. (JP) 2025-07-03 US disclosed
US-20250213433-A1 SELF-ADHESIVE COMPOSITE RESIN FOR DENTAL USE KURARAY NORITAKE DENTAL INC. (JP) 2025-07-03 US disclosed
EP-4578439-A1 DENTAL ADHESIVE COMPOSITION Kuraray Noritake Dental Inc. (JP) 2025-07-02 EP disclosed
EP-0738928-A2 Visible-ray polymerization initiator and visible-ray polymerizable composition TOKUYAMA CORPORATION (JP) 1996-10-23 EP disclosed
EP-0636939-A2 Photoinitiator compositions and photosensitive materials using the same HITACHI CHEMICAL COMPANY, LTD. (JP) 1995-02-01 EP disclosed
US-5153236-A Comprising an N-aryl-alpha-amino acid and a photosensitizer such as a thixoanthone, isoalloxazine or coumarine; high sensitivity to UV and visible light; storage stability; photoresists; relief images HITACHI CHEMICAL CO., LTD. (JP) 1992-10-06 US disclosed
US-4950581-A HIGH PHOTOSENSITIVITY; USING PHOTOINITIATOR FUJI PHOTO FILM CO., LTD. (JP) 1990-08-21 US disclosed
US-4948694-A CONTAINING PHOTOINITIATOR COMPRISING CAMPHORQUINONE AND COUMARIN DERIVATIVE; SENSITIVITY, STORAGE STABILITY CANON KABUSHIKI KAISHA (JP) 1990-08-14 US disclosed
US-4366228-A 3-KETOCOUMARIN DERIVATIVES AS PHOTOSENSITIZERS; ALPHA-PHENYLOXYALKYLENECARBOXYLIC ACIDS AS ACTIVATORS; HIGH SPEED EASTMAN KODAK COMPANY (US) 1982-12-28 US disclosed
US-4289844-A 3-KETO-COUMARIN DERIVATIVES, HIGH SPEED EASTMAN KODAK COMPANY (US) 1981-09-15 US disclosed
EP-0022188-A2 Co-initiator compositions for photopolymerization containing 3-acyl-substituted coumarins, photopolymerizable composition and photographic element EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1981-01-14 EP disclosed
US-4152159-A ACRYLIC ESTER POLYMERS EASTMAN KODAK COMPANY (US) 1979-05-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250213433-A1 SELF-ADHESIVE COMPOSITE RESIN FOR DENTAL USE CDH1, MACF1, ICAM1 ALDH1A1 695/4885KDM4E 3559/4885RAB9A 1260/4885
US-12527725-B2 Solvent-free dental adhesive composition CDH1, ITGA1, ITGB8 ALDH1A1 1885/4885KDM4E 2952/4885RAB9A 1701/4885
US-12465559-B2 Fluorescent curable dental composition and cured product thereof BRD1, TBCA, BAZ1A ALDH1A1 1780/4885KDM4E 1086/4885RAB9A 2558/4885
US-12564543-B2 Dental composition CAD, ARCN1, MAT1A ALDH1A1 306/4885KDM4E 2118/4885RAB9A 2847/4885
US-12622847-B2 Organosilicon compound and dental composition containing same MSL1, ITGA1, ITGAL ALDH1A1 668/4885KDM4E 2312/4885RAB9A 3519/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.