SCHEMBL20355291

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29559668	1.00	KIF11 (0.42)	KIF11TP53MAPTPRKAB2PRKAG1
	SCHEMBL27035954	0.89	TRPV4 (0.53)	KIF11TP53MAPTPRKAB2PRKAG1
	SCHEMBL20287858	0.83	PRKAB2 (0.37)	TP53MAPTPRKAB2PRKAG1PRKAA2
	SCHEMBL20354730	0.80	MEN1 (0.47)	KIF11MAPTHTR2ANR3C1NR3C2
	SCHEMBL30684580	0.78	GPR84 (0.51)	TP53TRPV4GSK3BDYRK1APOLB
	SCHEMBL17850497	0.78	GPR84 (0.51)	TP53TRPV4GSK3BDYRK1APOLB
	SCHEMBL20339031	0.77	CYP2A6 (0.51)	CDK1JAK2GSK3BCDK5
	SCHEMBL20355068	0.77	GPR84 (0.50)	HTR2A
	SCHEMBL20355378	0.76	MAPT (0.55)	TP53MAPTPRKAB2PRKAG1PRKAA2
	SCHEMBL27035966	0.76	HTR3E (0.47)	MAPTPRKAB2PRKAG1PRKAA2PRKAA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.