Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 4/20 | 0.39 |
| ▸ | AURKA | O14965 | 2/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GSK3A | P49840 | 2/20 | 0.37 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | GBA1 | P04062 | 2/20 | 0.37 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.37 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20414970 | 0.84 | USP1 (0.38) | NTRK1AURKAAURKBMAPTMEN1 | |
| SCHEMBL786507 | 0.80 | MAPT (0.48) | NTRK1AURKAAURKBMAPTMEN1 | |
| SCHEMBL802007 | 0.75 | AURKA (0.69) | NTRK1AURKAAURKBGSK3AGSK3B | |
| SCHEMBL20411749 | 0.74 | ABCG2 (0.46) | NTRK1AURKAAURKBMEN1KMT2A | |
| SCHEMBL8817528 | 0.74 | TGFBR1 (0.48) | GLA | |
| SCHEMBL802193 | 0.74 | GSK3B (0.69) | NTRK1AURKAAURKBMAPTMEN1 | |
| SCHEMBL20411752 | 0.73 | TP53 (0.49) | AURKAAURKBMAPTMEN1KMT2A | |
| SCHEMBL20411748 | 0.72 | ABCC8 (0.34) | MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14529444 | 0.72 | ACHE (0.49) | MAPTMEN1KMT2AGBA1POLB | |
| SCHEMBL863315 | 0.71 | ALPL (0.41) | MAPTMEN1KMT2AMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180212161-A1 | IRIDIUM COMPLEX AND ORGANIC LIGHT-EMITTING DIODE USING THE SAME | NATIONAL TSING HUA UNIVERSITY (TW) | 2018-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180212161-A1 | IRIDIUM COMPLEX AND ORGANIC LIGHT-EMITTING DIODE USING THE SAME | OCIAD1, OGFOD1, OGDH | NTRK1 4528/4885AURKA 2509/4885AURKB 1385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.