SCHEMBL20446010

SCHEMBL20446010

C=CC(=O)N[C@@H](Cc1ccc(N)cc1)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.53
MME P08473 7/20 0.47
PPARG P37231 2/20 0.43
NOS2 P35228 1/20 0.43
ACE2 Q9BYF1 5/20 0.43
ACE P12821 4/20 0.43
CPA1 P15085 3/20 0.43
NAALAD2 Q9Y3Q0 2/20 0.43
SOAT1 P35610 1/20 0.43
FOLH1 Q04609 1/20 0.43
NPSR1 Q6W5P4 1/20 0.42
PTPN1 P18031 1/20 0.42
CA1 P00915 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20446011 1.00 CA2 (0.53) CA2MMEPPARGNOS2ACE2
SCHEMBL30511891 0.86 FOLH1 (0.57) CA2MMENOS2ACE2ACE
SCHEMBL1097344 0.86 FOLH1 (0.57) CA2MMENOS2ACE2ACE
SCHEMBL1097343 0.86 FOLH1 (0.57) CA2MMENOS2ACE2ACE
SCHEMBL1135183 0.86 MME (0.58) MMENOS2ACE2ACECPA1
SCHEMBL29214532 0.86 MME (0.58) MMENOS2ACE2ACECPA1
SCHEMBL1135185 0.86 MME (0.58) MMENOS2ACE2ACECPA1
SCHEMBL31256909 0.82 PPID (0.50) NOS2
SCHEMBL29904332 0.81 PPARG (0.49) CA2MMEPPARGNOS2ACE2
SCHEMBL20578232 0.81 CA2 (0.58) CA2MMEACE2ACECPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12558432-B2 Biocompatible polymeric drug carriers for delivering active agents CIS BIOPHARMA AG (CH) 2026-02-24 US disclosed
US-20220409737-A1 BIOCOMPATIBLE POLYMERIC DRUG CARRIERS FOR DELIVERING ACTIVE AGENTS CIS BIOPHARMA AG (CH) 2022-12-29 US disclosed
EP-4051320-A1 BIOCOMPATIBLE POLYMERIC DRUG CARRIERS FOR DELIVERING ACTIVE AGENTS CIS Pharma AG (CH) 2022-09-07 EP disclosed
CN-114641316-A Biocompatible polymeric drug carriers for delivery of active agents CIS制药股份公司 2022-06-17 CN disclosed
US-11008414-B2 Polymer materials for contact lens applications CIS PHARMA AG (CH) 2021-05-18 US disclosed
US-20210128735-A1 BIOCOMPATIBLE COPOLYMER CONTAINING MULTIPLE ACTIVE AGENT MOLECULES CIS BIOPHARMA AG (CH) 2021-05-06 US disclosed
WO-2021084087-A1 BIOCOMPATIBLE POLYMERIC DRUG CARRIERS FOR DELIVERING ACTIVE AGENTS CIS PHARMA AG (CH) 2021-05-06 WO disclosed
EP-3790590-A1 BIOCOMPATIBLE COPOLYMER CONTAINING MULTIPLE ACTIVE AGENT MOLECULES CIS Pharma AG (CH) 2021-03-17 EP disclosed
CN-112088016-A Biocompatible copolymers containing multiple active agent molecules 化工研究所有限公司 2020-12-15 CN disclosed
US-20200283560-A1 New polymer materials for contact lens applications CIS PHARMA AG (CH) 2020-09-10 US disclosed
WO-2019215207-A1 BIOCOMPATIBLE COPOLYMER CONTAINING MULTIPLE ACTIVE AGENT MOLECULES CIS PHARMA AG (CH) 2019-11-14 WO disclosed
EP-3356433-B1 NEW POLYMER MATERIALS FOR CONTACT LENS APPLICATIONS CIS PHARMA AG (CH) 2019-09-18 EP disclosed
EP-3356433-A1 NEW POLYMER MATERIALS FOR CONTACT LENS APPLICATIONS CIS Pharma AG (CH) 2018-08-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12558432-B2 Biocompatible polymeric drug carriers for delivering active agents MSR1, CD47, SLC43A1 CA2 78/4885MME 2405/4885PPARG 4321/4885
US-20220409737-A1 BIOCOMPATIBLE POLYMERIC DRUG CARRIERS FOR DELIVERING ACTIVE AGENTS CD47, DNPEP, MSR1 CA2 236/4885MME 426/4885PPARG 4182/4885
US-20210128735-A1 BIOCOMPATIBLE COPOLYMER CONTAINING MULTIPLE ACTIVE AGENT MOLECULES LNPEP, PAICS, CD47 CA2 760/4885MME 741/4885PPARG 3190/4885
US-20200283560-A1 New polymer materials for contact lens applications CRYAA, CRYAB, BCAT1 CA2 1512/4885MME 2794/4885PPARG 3372/4885
US-11008414-B2 Polymer materials for contact lens applications CRYAA, BCAT1, CRYAB CA2 1537/4885MME 2887/4885PPARG 3350/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.