Sugi Predict

Sugi Predict / Compounds / SCHEMBL204616

SCHEMBL204616

SCHEMBL204616

COC(C)=C(C(=O)O)c1ccccc1Oc1cccc(Oc2ncc(C)cn2)c1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 2/20 0.40
▸ KDM4E B2RXH2 1/20 0.40
▸ POLB P06746 1/20 0.40
▸ GAA P10253 2/20 0.39
▸ TSHR P16473 1/20 0.39
▸ MTNR1B P49286 1/20 0.39
▸ CYP1A2 P05177 3/20 0.39
▸ CYP3A4 P08684 2/20 0.39
▸ CYP2C9 P11712 2/20 0.39
▸ CYP2C19 P33261 2/20 0.39
▸ MEN1 O00255 4/20 0.38
▸ KMT2A Q03164 4/20 0.38
▸ HPGDS O60760 1/20 0.38
▸ RAB9A P51151 1/20 0.38
▸ HTT P42858 1/20 0.38
▸ CTNNB1 P35222 1/20 0.36
▸ MAPK1 P28482 1/20 0.36
▸ HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL205379 0.90 MEN1 (0.49) KDM4EPOLBGAATSHRMTNR1B
SCHEMBL204615 0.90 TSHR (0.41) ALDH1A1KDM4EPOLBGAATSHR
SCHEMBL202626 0.84 KDM4E (0.57) KDM4EPOLBGAAMTNR1BCYP1A2
SCHEMBL9049905 0.83 MTNR1B (0.37) ALDH1A1KDM4EPOLBGAATSHR
SCHEMBL203538 0.82 LMNA (0.51) ALDH1A1KDM4EPOLBGAAMTNR1B
SCHEMBL2856609 0.81 KDM4E (0.40) ALDH1A1KDM4EPOLBGAATSHR
SCHEMBL8603089 0.81 LMNA (0.47) ALDH1A1KDM4EPOLBGAAMTNR1B
SCHEMBL204217 0.81 LMNA (0.47) ALDH1A1KDM4EPOLBGAAMTNR1B
SCHEMBL203718 0.81 CTNNB1 (0.54) ALDH1A1KDM4EGAATSHRMEN1
SCHEMBL204355 0.81 L3MBTL1 (0.44) KDM4EPOLBMTNR1BMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12464971-B2 Sowing device and method for treating seeds during planting SYNGENTA CROP PROTECTION AG (CH) 2025-11-11 — — US disclosed
US-20250241304-A1 FUNGICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2025-07-31 — — US disclosed
US-11185074-B2 Microbiocidal quinoline (thio)carboxamide derivatives SYNGENTA PARTICIPATIONS AG (CH) 2021-11-30 — — US disclosed
US-20150144027-A1 PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING THE SAME KOPPERS INC. (F/K/A KOPPERS INDUSTRIES, INC.) 2015-05-28 — — US disclosed
US-20130324457-A1 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF AVENTIS AGRICULTURE (FR) 2013-12-05 — — US disclosed
US-8445519-B2 1-aryl-5-alkyl pyrazole derivative compounds, processes of making and methods of using thereof AVENTIS AGRICULTURE (FR) 2013-05-21 — — US disclosed
US-8409627-B2 Particulate wood preservative and method for producing the same OSMOSE, INC. (US) 2013-04-02 — — US disclosed
US-8088801-B2 Aryloazol-2-yl cyanoethylamino compounds, method of making and method of using thereof MERIAL LIMITED (US) 2012-01-03 — — US disclosed
US-20100249194-A1 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF MERIAL, INC. 2010-09-30 — — US disclosed
EP-1755841-B1 TREATMENT OF WOOD WITH AN INJECTABLE WOOD PRESERVATIVE SLURRY HAVING BIOCIDAL PARTICLES OSMOSE INC (US) 2010-09-15 — — EP disclosed
WO-1997008140-A1 N-SULFONYLIMINODITHIO COMPOUNDS USEFUL FOR PLANT AND MATERIAL PROTECTION BAYER AKTIENGESELLSCHAFT (DE) 1997-03-06 — — WO disclosed
WO-1997001547-A1 BENZAZOLE DERIVATIVES WITH MICROBIOCIDAL PROPERTIES BAYER AKTIENGESELLSCHAFT (DE) 1997-01-16 — — WO disclosed
EP-0750542-A1 COMBINATIONS OF ACTIVE INSECTICIDE SUBSTANCES BAYER AG (DE) 1997-01-02 — — EP disclosed
WO-1996029314-A1 THIOCARBAMOYL COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 1996-09-26 — — WO disclosed
EP-0730517-A1 TIMBER PRESERVATIVE CONTAINING A COPPER COMPOUND BAYER AG (DE) 1996-09-11 — — EP disclosed
WO-1996025044-A1 S-ARYL CYANIMIDOTHIO COMPOUNDS FOR MATERIAL PROTECTION BAYER AKTIENGESELLSCHAFT (DE) 1996-08-22 — — WO disclosed
WO-1996010915-A1 INSECTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1996-04-18 — — WO disclosed
WO-1995024997-A1 COMBINATIONS OF ACTIVE INSECTICIDE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 1995-09-21 — — WO disclosed
WO-1995014558-A1 TIMBER PRESERVATIVE CONTAINING A COPPER COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1995-06-01 — — WO disclosed
WO-1995011786-A1 TIMBER PROTECTING MEDIUM CONTAINING A COPPER COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1995-05-04 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100249194-A1 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF CBR3, CBR1, NR5A2 ALDH1A1 3762/4885KDM4E 3120/4885POLB 4213/4885
US-11185074-B2 Microbiocidal quinoline (thio)carboxamide derivatives IFNG, TLR1, IDO1 ALDH1A1 1059/4885KDM4E 1828/4885POLB 1822/4885
US-20250241304-A1 FUNGICIDAL COMPOUNDS CYP1B1, CYP51A1, CYP1A1 ALDH1A1 208/4885KDM4E 852/4885POLB 4747/4885
US-20130324457-A1 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF CBR3, CBR1, NR5A2 ALDH1A1 3762/4885KDM4E 3120/4885POLB 4213/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.