Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20465188 | 0.88 | RAB9A (0.47) | KMT2AKDM4EMEN1MAPTHPGD | |
| SCHEMBL18440690 | 0.86 | RORC (0.45) | KMT2AKDM4EGPR35ALDH1A1ACSS2 | |
| SCHEMBL18440902 | 0.76 | RAB9A (0.43) | KMT2AKDM4EMEN1MAPTHPGD | |
| SCHEMBL20465195 | 0.76 | RORC (0.60) | — | |
| SCHEMBL14549402 | 0.74 | KMT2A (0.51) | KMT2AKDM4ETHRBMEN1MAPT | |
| SCHEMBL9613337 | 0.74 | GPR35 (0.62) | KMT2AKDM4ETHRBMEN1MAPT | |
| SCHEMBL19360617 | 0.74 | SRD5A2 (0.49) | KMT2AKDM4EGPR35ALDH1A1ACSS2 | |
| SCHEMBL20465147 | 0.71 | SRD5A2 (0.48) | KMT2AKDM4ETHRBMEN1MAPT | |
| SCHEMBL5889499 | 0.69 | ALDH1A1 (0.56) | KDM4EHPGDGPR35ALDH1A1HCAR3 | |
| SCHEMBL28219655 | 0.68 | ALDH1A1 (0.48) | KMT2AKDM4ETHRBMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180222860-A1 | MODULATORS OF ROR-GAMMA | VITAE PHARMACEUTICALS, LLC | 2018-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180222860-A1 | MODULATORS OF ROR-GAMMA | RORB, RORC, RORA | KMT2A 2604/4885KDM4E 3259/4885THRB 55/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.