Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4821699 | 0.94 | — | — | |
| Water SCHEMBL28239912 | 0.89 | — | — | |
| SCHEMBL8840175 | 0.89 | — | — | |
| SCHEMBL26885 | 0.88 | — | — | |
| SCHEMBL9398161 | 0.88 | — | — | |
| SCHEMBL9126752 | 0.88 | — | — | |
| SCHEMBL9701931 | 0.88 | — | — | |
| SCHEMBL17236 | 0.88 | — | — | |
| SCHEMBL14993262 | 0.84 | — | — | |
| Zinc Ion SCHEMBL5468291 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10307511-B2 | Bioactive composites of polymer and glass and method for making same | ORTHOVITA, INC. (US) | 2019-06-04 | — | — | US | disclosed |
| US-20190125931-A1 | Bioactive Load-bearing Composites | ORTHOVITA, INC. | 2019-05-02 | — | — | US | disclosed |
| US-10195308-B2 | Bioactive load-bearing composites | ORTHOVITA, INC. (US) | 2019-02-05 | — | — | US | disclosed |
| US-20170232147-A1 | BIOACTIVE COMPOSITES OF POLYMER AND GLASS AND METHOD FOR MAKING SAME | STRYKER CORPORATION | 2017-08-17 | — | — | US | disclosed |
| US-9662821-B2 | Bioactive composites of polymer and glass and method for making same | ORTHOVITA, INC. (US) | 2017-05-30 | — | — | US | disclosed |
| US-20160279294-A1 | BIOACTIVE LOAD-BEARING COMPOSITES | STRYKER CORPORATION | 2016-09-29 | — | — | US | disclosed |
| US-9381275-B2 | Bioactive load-bearing composites | ORTHOVITA, INC. (US) | 2016-07-05 | — | — | US | disclosed |
| US-20150273751-A1 | BIOACTIVE COMPOSITES OF POLYMER AND GLASS AND METHOD FOR MAKING SAME | STRYKER CORPORATION | 2015-10-01 | — | — | US | disclosed |
| US-20150133578-A1 | BIOACTIVE LOAD-BEARING COMPOSITES | STRYKER CORPORATION | 2015-05-14 | — | — | US | disclosed |
| US-8968797-B2 | Bioactive load-bearing composites | ORTHOVITA, INC. (US) | 2015-03-03 | — | — | US | disclosed |
| US-8778378-B2 | Bioactive antibacterial bone graft materials | ORTHOVITA, INC. (US) | 2014-07-15 | — | — | US | disclosed |
| US-8597675-B2 | Bioactive load-bearing composites | ORTHOVITA, INC. (US) | 2013-12-03 | — | — | US | disclosed |
| WO-2013116057-A1 | BIOACTIVE ANTIBACTERIAL BONE GRAFT MATERIALS CONTAINING SILVER | ORTHOVITA, INC. (US) | 2013-08-08 | — | — | WO | disclosed |
| US-20130202670-A1 | BIOACTIVE ANTIBACTERIAL BONE GRAFT MATERIALS CONTAINING SILVER | ORTHOVITA, INC. (US) | 2013-08-08 | — | — | US | disclosed |
| US-20120237568-A1 | Bioactive Load-Bearing Composites | Stryker Orthobiologics | 2012-09-20 | — | — | US | disclosed |
| EP-2381897-A1 | BIOACTIVE COMPOSITES OF POLYMER AND GLASS AND METHOD FOR MAKING SAME | Orthovita, Inc. (US) | 2011-11-02 | — | — | EP | disclosed |
| US-20110150963-A1 | BIOACTIVE ANTIBACTERIAL BONE GRAFT MATERIALS | STRYKER CORPORATION | 2011-06-23 | — | — | US | disclosed |
| WO-2010077948-A1 | BIOACTIVE COMPOSITES OF POLYMER AND GLASS AND METHOD FOR MAKING SAME | ORTHOVITA, INC. (US) | 2010-07-08 | — | — | WO | disclosed |
| US-20100168798-A1 | BIOACTIVE COMPOSITES OF POLYMER AND GLASS AND METHOD FOR MAKING SAME | ORTHOVITA, INC. | 2010-07-01 | — | — | US | disclosed |
| US-20100129416-A1 | BIOACTIVE LOAD-BEARING COMPOSITES | ORTHOVITA, INC (US) | 2010-05-27 | — | — | US | disclosed |