Known targets — ChEMBL curated mechanism
ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB known ✓ | P09619 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.35 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.35 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23219318 | 0.85 | TOP2A (0.40) | KIF11TP53MAPTALDH1A1HPGD | |
| SCHEMBL20540672 | 0.81 | GAA (0.37) | KIF11TP53MAPTALDH3A1GAA | |
| SCHEMBL12800982 | 0.78 | TOP2A (0.40) | KIF11TP53MAPTALDH1A1HPGD | |
| SCHEMBL30876355 | 0.78 | TOP2A (0.40) | KIF11TP53MAPTALDH1A1HPGD | |
| SCHEMBL15415465 | 0.76 | ALDH3A1 (0.50) | TP53ALDH3A1ALDH1A1HPGDHTT | |
| SCHEMBL26342598 | 0.74 | CDK4 (0.36) | TP53MAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL12800995 | 0.73 | L3MBTL1 (0.50) | TP53MAPTALDH3A1ALDH1A1HPGD | |
| Carbazole SCHEMBL1352178 | 0.73 | EGFR (0.54) | KIF11MAPTALDH1A1HPGDHTT | |
| SCHEMBL15631669 | 0.73 | KDM4E (0.35) | TP53MAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL17993422 | 0.72 | L3MBTL1 (0.41) | TP53MAPTALDH1A1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11591356-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2023-02-28 | — | — | US | disclosed |
| US-20220119434-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2022-04-21 | — | — | US | disclosed |
| US-10975113-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2021-04-13 | — | — | US | disclosed |
| US-20180305384-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2018-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11591356-B2 | Organic electroluminescent materials and devices | L1CAM, SOD1, EPCAM | PDGFRB 4442/4885KIF11 2633/4885TP53 2469/4885 |
| US-20220119434-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | L1CAM, SOD1, EPCAM | PDGFRB 4334/4885KIF11 2948/4885TP53 2785/4885 |
| US-10975113-B2 | Organic electroluminescent materials and devices | OSBPL3, OCIAD1, OSBP | PDGFRB 4519/4885KIF11 3269/4885TP53 4055/4885 |
| US-20180305384-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | OSBP, OCIAD1, OCIAD2 | PDGFRB 4551/4885KIF11 3551/4885TP53 3886/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.