SCHEMBL2054539

SCHEMBL2054539

CON(C)C(=O)C(C)(C)C

nearest known ligand 0.32

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MLYCD O95822 1/20 0.32
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
TDP1 Q9NUW8 1/20 0.31
PKM P14618 1/20 0.31
RAB9A P51151 1/20 0.31
CYP3A4 P08684 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12444727 0.85
SCHEMBL1818086 0.79 MLYCD (0.42) MLYCD
SCHEMBL25691634 0.79 MLYCD (0.31) MLYCD
SCHEMBL63072 0.79 MLYCD (0.31) MLYCD
SCHEMBL29684122 0.79 NOTUM (0.43) MLYCDMEN1KMT2ATDP1PKM
SCHEMBL23930073 0.79 MLYCD (0.38) MLYCD
SCHEMBL2278324 0.79 MLYCD (0.31) MLYCD
SCHEMBL1161728 0.76 MLYCD (0.39) MLYCDMEN1KMT2ATDP1PKM
SCHEMBL28976107 0.76 L3MBTL1 (0.37) MLYCDMEN1KMT2ATDP1PKM
SCHEMBL1538117 0.75 RIPK1 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12583878-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2026-03-24 US disclosed
US-12460128-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2025-11-04 US disclosed
US-20250333421-A1 PYRIDAZINES OR 1,2,4-TRIAZINES SUBSTITUTED BY SPIROCYCLIC AMINES JANSSEN PHARMACEUTICA NV (BE) 2025-10-30 US disclosed
US-20240066027-A1 NOVEL PAR-2 INHIBITORS DOMAIN THERAPEUTICS (FR) 2024-02-29 US disclosed
EP-4255904-A2 NOVEL PAR-2 INHIBITORS Domain Therapeutics (FR) 2023-10-11 EP disclosed
US-20230159438-A1 ARYLAMIDES AND METHODS OF USE THEREOF GENZYME CORPORATION 2023-05-25 US disclosed
US-20230147360-A1 ARYLAMIDES AND METHODS OF USE THEREOF GENZYME CORPORATION 2023-05-11 US disclosed
US-20230128062-A1 AZABICYCLIC SUBSTITUTED OXASPIRO DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF SHANGHAI HAIYAN PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) 2023-04-27 US disclosed
US-20230015308-A1 SUBSTITUTED THIAZOLE AROMATIC RING-BASED COMPOUND AND PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF QINGDAO KINGAGROOT CHEMICAL COMPOUND CO., LTD. (CN) 2023-01-19 US disclosed
WO-2022117882-A2 NOVEL PAR-2 INHIBITORS DOMAIN THERAPEUTICS (FR) 2022-06-09 WO disclosed
US-20080004273-A1 Inhibitors of protein tyrosine kinase activity METHYLGENE, INC. (CA) 2008-01-03 US disclosed
US-20070004675-A1 Inhibitors of VEGF receptor and HGF receptor signaling METHYLGENE, INC. 2007-01-04 US disclosed
US-7125877-B2 Benzimidazole derivatives BANYU PHARMACEUTICAL CO., LTD. (JP) 2006-10-24 US disclosed
EP-1505063-A1 BENZIMIDAZOLE DERIVATIVES BANYU PHARMACEUTICAL CO., LTD. (JP) 2005-02-09 EP disclosed
US-20030236267-A1 Benzimidazole derivatives MSD K.K. (JP) 2003-12-25 US disclosed
EP-0731803-A4 NOVEL FURANODIAZEPINES MERCK & CO INC (US) 1997-06-18 EP disclosed
EP-0731803-A1 NOVEL FURANODIAZEPINES MERCK & CO. INC. (US) 1996-09-18 EP disclosed
US-5453424-A Furanodiazepines MERCK & CO., INC. (US) 1995-09-26 US disclosed
WO-1995014695-A1 NOVEL FURANODIAZEPINES MERCK & CO., INC. (US) 1995-06-01 WO disclosed
EP-0409418-A1 Heterocyclic tertiary alcohols IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-01-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12460128-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, ICOSLG MLYCD 8/4885MEN1 2869/4885KMT2A 2410/4885
US-20070004675-A1 Inhibitors of VEGF receptor and HGF receptor signaling HGF, MET, FLT1 MLYCD 4030/4885MEN1 3655/4885KMT2A 3391/4885
US-20230128062-A1 AZABICYCLIC SUBSTITUTED OXASPIRO DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF CYP4A11, CYP51A1, CYP4F11 MLYCD 2525/4885MEN1 351/4885KMT2A 3586/4885
US-12583878-B2 Organic electroluminescent materials and devices SOD1, SSB, ROS1 MLYCD 1229/4885MEN1 4357/4885KMT2A 2517/4885
US-20230147360-A1 ARYLAMIDES AND METHODS OF USE THEREOF CFTR, AADAC, ARSA MLYCD 407/4885MEN1 4477/4885KMT2A 2884/4885
US-20030236267-A1 Benzimidazole derivatives OPRL1, GPR119, NPBWR1 MLYCD 2462/4885MEN1 1634/4885KMT2A 3564/4885
US-20230159438-A1 ARYLAMIDES AND METHODS OF USE THEREOF CFTR, AADAC, ARSA MLYCD 407/4885MEN1 4477/4885KMT2A 2884/4885
US-20230015308-A1 SUBSTITUTED THIAZOLE AROMATIC RING-BASED COMPOUND AND PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF WEE1, CBR3, GLRX3 MLYCD 1423/4885MEN1 4484/4885KMT2A 3228/4885
US-20240066027-A1 NOVEL PAR-2 INHIBITORS F2RL1, F2R, F2RL3 MLYCD 4027/4885MEN1 1034/4885KMT2A 2201/4885
US-20080004273-A1 Inhibitors of protein tyrosine kinase activity HGF, ERBB2, MET MLYCD 4000/4885MEN1 3231/4885KMT2A 2353/4885
US-20250333421-A1 PYRIDAZINES OR 1,2,4-TRIAZINES SUBSTITUTED BY SPIROCYCLIC AMINES MEN1, MLLT1, MPL MLYCD 627/4885MEN1 1/4885KMT2A 54/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.