Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 8/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.35 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20633233 | 0.87 | KMT2A (0.36) | FYNTRPA1TRPV3TRPV4ADORA2A | |
| SCHEMBL20632804 | 0.85 | KDM1A (0.38) | SCN9AFYNTRPA1TRPV3TRPV4 | |
| SCHEMBL20632477 | 0.83 | KDM1A (0.34) | SCN9ATRPV3ITGB3ITGA2BKDM1A | |
| SCHEMBL20633441 | 0.82 | FYN (0.39) | FYNTRPV4KDM1A | |
| SCHEMBL20633005 | 0.82 | LMNA (0.38) | FYNKDM1ACNR2 | |
| SCHEMBL20632024 | 0.82 | RHOA (0.47) | FYNARCFTRITGB3ITGA2B | |
| SCHEMBL20632705 | 0.82 | PHGDH (0.41) | TRPV3KDM1ACNR2 | |
| SCHEMBL20632673 | 0.82 | CA2 (0.36) | FYNCFTRADORA2AKDM1ACNR2 | |
| SCHEMBL20632358 | 0.81 | KDM1A (0.33) | SCN9ATRPV3KDM1ACNR2 | |
| SCHEMBL20633162 | 0.81 | AURKA (0.38) | FYNKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2997029-B1 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS | GLAXOSMITHKLINE LLC (US) | 2019-01-09 | — | — | EP | disclosed |