SCHEMBL2064675

SCHEMBL2064675

COC(c1cc([B]c2cc(C(OC)(C(F)(F)F)C(F)(F)F)cc(C(OC)(C(F)(F)F)C(F)(F)F)c2)cc(C(OC)(C(F)(F)F)C(F)(F)F)c1)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.33
NR1H3 Q13133 1/20 0.33
RORC P51449 2/20 0.31
NR1I2 O75469 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14453638 0.80 IDO1 (0.39) NR1H2NR1H3RORCNR1I2
SCHEMBL29402219 0.77 NR1H2 (0.37) NR1H2NR1H3RORCNR1I2
SCHEMBL10876573 0.77 NR1H2 (0.34) NR1H2NR1H3RORCNR1I2
SCHEMBL1902850 0.77 NR1H2 (0.34) NR1H2NR1H3RORCNR1I2
SCHEMBL1902847 0.77 NR1H2 (0.37) NR1H2NR1H3RORCNR1I2
SCHEMBL985526 0.75 NR1H2 (0.36) NR1H2NR1H3RORCNR1I2
SCHEMBL2064676 0.75 NR1H2 (0.33) NR1H2NR1H3RORCNR1I2
SCHEMBL1037335 0.75 NR1H2 (0.36) NR1H2NR1H3RORCNR1I2
SCHEMBL10876412 0.75 MEN1 (0.41) NR1H2NR1H3RORC
SCHEMBL10878692 0.74 PGK1 (0.42) NR1H2NR1H3RORCNR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240164993-A1 ORGANOSILICON COMPOUND AND DENTAL COMPOSITION CONTAINING SAME KURARAY NORITAKE DENTAL INC. (JP) 2024-05-23 US disclosed
US-20230381066-A1 DENTAL CURABLE COMPOSITION HAVING GOOD COLOR COMPATIBILITY KURARAY NORITAKE DENTAL INC. (JP) 2023-11-30 US disclosed
EP-4268791-A1 ORGANOSILICON COMPOUND AND DENTAL COMPOSITION CONTAINING SAME Kuraray Noritake Dental Inc. (JP) 2023-11-01 EP disclosed
EP-4238546-A1 DENTAL CURABLE COMPOSITION HAVING GOOD COLOR COMPATIBILITY Kuraray Noritake Dental Inc. (JP) 2023-09-06 EP disclosed
US-20230049373-A1 PASTE-LIKE COMPOSITION FOR DENTAL USE, AND METHOD FOR PRODUCING THE SAME KURARAY NORITAKE DENTAL INC. (JP) 2023-02-16 US disclosed
EP-3782598-B1 ADHESIVE COMPOSITION FOR DENTAL USE KURARAY NORITAKE DENTAL INC (JP) 2023-02-15 EP disclosed
US-20230040426-A1 DENTAL RESTORATION MATERIAL COMPOSITION KURARAY NORITAKE DENTAL INC. (JP) 2023-02-09 US disclosed
US-11547639-B2 Dental composition containing platinum nanoparticles KURARAY NORITAKE DENTAL INC. (JP) 2023-01-10 US disclosed
EP-3900694-A1 DENTAL ADHESIVE COMPOSITION Kuraray Noritake Dental Inc. (JP) 2021-10-27 EP disclosed
US-20210145701-A1 ADHESIVE COMPOSITION FOR DENTAL USE KURARAY NORITAKE DENTAL INC. (JP) 2021-05-20 US disclosed
EP-3782598-A1 ADHESIVE COMPOSITION FOR DENTAL USE Kuraray Noritake Dental Inc. (JP) 2021-02-24 EP disclosed
US-20200390661-A1 DENTAL COMPOSITION CONTAINING PLATINUM NANOPARTICLES KURARAY NORITAKE DENTAL INC. (JP) 2020-12-17 US disclosed
EP-3725288-A1 DENTAL COMPOSITION CONTAINING PLATINUM NANOPARTICLES Kuraray Noritake Dental Inc. (JP) 2020-10-21 EP disclosed
EP-2070935-B1 NOVEL COMPOUND, COMPOSITION COMPRISING THE SAME, AND PROCESS FOR PRODUCTION OF POLYMERIZABLE AMIDE KURARAY NORITAKE DENTAL INC (JP) 2015-01-07 EP disclosed
US-8148571-B2 Compound, composition comprising the same, and process for production of polymerizable amide KURARAY MEDICAL INC. (JP) 2012-04-03 US disclosed
US-20100076157-A1 NOVEL COMPOUND, COMPOSITION COMPRISING THE SAME, AND PROCESS FOR PRODUCTION OF POLYMERIZABLE AMIDE KURARAY MEDICAL INC. (JP) 2010-03-25 US disclosed
EP-2070935-A1 NOVEL COMPOUND, COMPOSITION COMPRISING THE SAME, AND PROCESS FOR PRODUCTION OF POLYMERIZABLE AMIDE Kuraray Medical Inc. (JP) 2009-06-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230040426-A1 DENTAL RESTORATION MATERIAL COMPOSITION CAD, MAT2B, RER1 NR1H2 1430/4885NR1H3 1857/4885RORC 3723/4885
US-20100076157-A1 NOVEL COMPOUND, COMPOSITION COMPRISING THE SAME, AND PROCESS FOR PRODUCTION OF POLYMERIZABLE AMIDE H1-0, H1-4, H1-2 NR1H2 458/4885NR1H3 449/4885RORC 1772/4885
US-20230049373-A1 PASTE-LIKE COMPOSITION FOR DENTAL USE, AND METHOD FOR PRODUCING THE SAME PFN1, XRN2, FLNA NR1H2 4732/4885NR1H3 4826/4885RORC 4841/4885
US-20240164993-A1 ORGANOSILICON COMPOUND AND DENTAL COMPOSITION CONTAINING SAME MSL1, ITGA1, ASH2L NR1H2 1110/4885NR1H3 1223/4885RORC 3889/4885
US-20210145701-A1 ADHESIVE COMPOSITION FOR DENTAL USE PTK2, CDH1, ITGA1 NR1H2 4617/4885NR1H3 4334/4885RORC 4067/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.