Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.40 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PER2 | O15055 | 1/20 | 0.38 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.38 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | APLNR | P35414 | 2/20 | 0.38 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20679705 | 0.82 | ALDH1A1 (0.45) | SMN1; SMN2ALDH1A1NR3C1CNR2 | |
| SCHEMBL20679713 | 0.82 | PYCR1 (0.42) | SMN1; SMN2ALDH1A1PYCR1NR3C1HDAC6 | |
| SCHEMBL20679708 | 0.80 | APLNR (0.63) | BCL2A1SMN1; SMN2ALDH1A1APLNRPYCR1 | |
| SCHEMBL20679707 | 0.78 | CRHBP (0.47) | ALDH1A1PYCR1 | |
| SCHEMBL20679714 | 0.72 | SERPINE1 (0.40) | — | |
| SCHEMBL5923874 | 0.68 | ESR1 (0.57) | ESR1ESR2CNR1CNR2 | |
| SCHEMBL425354 | 0.66 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1NR3C1 | |
| SCHEMBL15246781 | 0.66 | RIPK1 (0.46) | KCNA5ESR1ESR2ATMPYCR1 | |
| SCHEMBL15672908 | 0.66 | MAOA (0.46) | KCNA5ATMPYCR1HDAC11HDAC8 | |
| SCHEMBL20847569 | 0.66 | HDAC6 (0.65) | KCNA5ATMPYCR1HDAC11HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10933409-B2 | Transition metal complex containing sulfonamide or amide group for olefin metathesis reaction and application thereof | SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) | 2021-03-02 | — | — | US | disclosed |
| US-10933409-B2 | Transition metal complex containing sulfonamide or amide group for olefin metathesis reaction and application thereof | SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) | 2021-03-02 | — | — | US | disclosed |
| US-20190030521-A1 | TRANSITION METAL COMPLEX CONTAINING SULFONAMIDE OR AMIDE GROUP FOR OLEFIN METATHESIS REACTION AND APPLICATION THEREOF | SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) | 2019-01-31 | — | — | US | disclosed |
| US-20190030521-A1 | TRANSITION METAL COMPLEX CONTAINING SULFONAMIDE OR AMIDE GROUP FOR OLEFIN METATHESIS REACTION AND APPLICATION THEREOF | SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) | 2019-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10933409-B2 | Transition metal complex containing sulfonamide or amide group for olefin metathesis reaction and application thereof | TST, NBAS, TRRAP | KCNA5 1490/4885BCL2A1 2233/4885ESR1 1587/4885 |
| US-20190030521-A1 | TRANSITION METAL COMPLEX CONTAINING SULFONAMIDE OR AMIDE GROUP FOR OLEFIN METATHESIS REACTION AND APPLICATION THEREOF | TST, NIT2, NBAS | KCNA5 1945/4885BCL2A1 1997/4885ESR1 1844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.