SCHEMBL2070026

SCHEMBL2070026

CC(=O)N(c1ccccc1)c1ccccc1-c1ccc(I)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.44
APAF1 O14727 2/20 0.44
LTB4R2 Q9NPC1 2/20 0.42
KMT2A Q03164 5/20 0.39
MEN1 O00255 4/20 0.39
TSHR P16473 1/20 0.39
NPSR1 Q6W5P4 4/20 0.39
TDP2 O95551 1/20 0.37
NSD2 O96028 1/20 0.37
CASP3 P42574 1/20 0.37
CACNA1B Q00975 1/20 0.37
APBA1 Q02410 1/20 0.37
HKDC1 Q2TB90 1/20 0.37
SENP8 Q96LD8 1/20 0.37
SENP7 Q9BQF6 1/20 0.37
SENP6 Q9GZR1 1/20 0.37
APOBEC3G Q9HC16 1/20 0.37
SAE1 Q9UBE0 1/20 0.37
UBA2 Q9UBT2 1/20 0.37
ALDH1A1 P00352 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4849735 0.82 NPSR1 (0.45) NPC1APAF1LTB4R2KMT2AMEN1
SCHEMBL4849374 0.80 NPSR1 (0.50) NPC1APAF1KMT2AMEN1TSHR
SCHEMBL5489120 0.79 MAPT (0.46) NPC1APAF1KMT2AMEN1TSHR
SCHEMBL23869918 0.77 NPSR1 (0.47) NPC1APAF1KMT2AMEN1TSHR
SCHEMBL4893753 0.75 SIGMAR1 (0.46) NPC1KMT2AMEN1NPSR1ALDH1A1
SCHEMBL10785562 0.75 NPSR1 (0.48) NPC1APAF1LTB4R2KMT2AMEN1
SCHEMBL741752 0.72 NPSR1 (0.64) NPC1APAF1KMT2AMEN1TSHR
SCHEMBL7985338 0.72 KMT2A (0.54) NPC1APAF1KMT2AMEN1TSHR
SCHEMBL4304234 0.72 EGFR (0.44) NPC1KMT2AMEN1TSHRRAB9A
SCHEMBL942431 0.70 NPC1 (0.47) NPC1APAF1KMT2AMEN1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1698613-B1 Tetramine compound and organic electroluminescence element HODOGAYA CHEMICAL CO LTD (JP) 2013-05-01 EP disclosed
US-7902402-B2 N,N'-bis(4-diphenylaminobiphenyl-4'-yl)-N,N'-diphenyl-4,4''-diamino-p-terphenyl; EL element comprises an anode, a hole transport layer, a light emitting layer, an electron transport layer and a cathode laminated sequentially on a substrate; displays; provides high luminance at low applied voltage HODOGAYA CHEMICAL CO., LTD. (JP) 2011-03-08 US disclosed
US-7897816-B2 N,N'-bis(4-diphenylaminobiphenyl-4'-yl)-N,N'-diphenyl-4,4''-diamino-p-terphenyl; EL element comprises an anode, a hole transport layer, a light emitting layer, an electron transport layer and a cathode laminated sequentially on a substrate; displays; provides high luminance at low applied voltage HODOGAYA CHEMICAL CO., LTD. (JP) 2011-03-01 US disclosed
US-7807274-B2 N,N'-bis(4-diphenylaminobiphenyl-4'-yl)-N,N'-diphenyl-4,4''-diamino-p-terphenyl; EL element comprises an anode, a hole transport layer, a light emitting layer, an electron transport layer and a cathode laminated sequentially on a substrate; displays; provides high luminance at low applied voltage HODOGAYA CHEMICAL CO., LTD. (JP) 2010-10-05 US disclosed
US-20100174115-A1 TETRAMINE COMPOUND AND ORGANIC EL DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2010-07-08 US disclosed
US-20100171080-A1 TETRAMINE COMPOUND AND ORGANIC EL DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2010-07-08 US disclosed
US-20070149816-A1 N,N'-bis(4-diphenylaminobiphenyl-4'-yl)-N,N'-diphenyl-4,4''-diamino-p-terphenyl; EL element comprises an anode, a hole transport layer, a light emitting layer, an electron transport layer and a cathode laminated sequentially on a substrate; displays; provides high luminance at low applied voltage HODOGAYA CHEMICAL CO., LTD. (JP) 2007-06-28 US disclosed
EP-1698613-A1 TETRAMINE COMPOUND AND ORGANIC EL DEVICE Hodogaya Chemical Co., Ltd. (JP) 2006-09-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070149816-A1 N,N'-bis(4-diphenylaminobiphenyl-4'-yl)-N,N'-diphenyl-4,4''-diamino-p-terphenyl; EL element comprises an anode, a hole transport layer, a light emitting layer, an electron transport layer and a cathode laminated sequentially on a substrate; displays; provides high luminance at low applied voltage SLC6A19, TEAD4, RPL19 NPC1 494/4885APAF1 3939/4885LTB4R2 661/4885
US-20100171080-A1 TETRAMINE COMPOUND AND ORGANIC EL DEVICE TTI1, ELF3, TERT NPC1 2025/4885APAF1 3543/4885LTB4R2 652/4885
US-20100174115-A1 TETRAMINE COMPOUND AND ORGANIC EL DEVICE TTI1, TERT, RIF1 NPC1 2040/4885APAF1 3400/4885LTB4R2 624/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.