SCHEMBL20734196

SCHEMBL20734196

c1ccc(B2N(c3ccccc3)B(c3ccccc3)N(c3ccccc3)B(c3cccc(-c4cccc(-c5c(-c6ccccc6)c(-c6ccccc6)c(-c6ccccc6)c(-c6ccccc6)c5-c5ccccc5)c4)c3)N2c2ccccc2)cc1

nearest known ligand 0.34

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.34
FAAH O00519 1/20 0.34
ALDH1A1 P00352 1/20 0.34
HSP90AA1 P07900 1/20 0.34
PKM P14618 1/20 0.34
ATM Q13315 1/20 0.34
MGLL Q99685 1/20 0.34
HTR1A P08908 1/20 0.33
HTR7 P34969 1/20 0.33
DCTPP1 Q9H773 1/20 0.31
ACMSD Q8TDX5 1/20 0.30
KMO O15229 1/20 0.30
MEN1 O00255 1/20 0.30
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30
OPRM1 P35372 1/20 0.30
OPRD1 P41143 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20180645 0.83 L3MBTL1 (0.37) HTTALDH1A1MEN1MAPTKMT2A
SCHEMBL20180755 0.81 FAAH (0.33) HTTFAAHALDH1A1HSP90AA1PKM
SCHEMBL20734197 0.80
SCHEMBL2484655 0.78 LMNA (0.36) ALDH1A1ATMMGLLMEN1GAA
SCHEMBL20180646 0.77 L3MBTL1 (0.47) HTTFAAHALDH1A1HSP90AA1PKM
SCHEMBL20734362 0.74 L3MBTL1 (0.41) HTTALDH1A1ATMMEN1MAPT
SCHEMBL20735422 0.74 FAAH (0.33) HTTFAAHALDH1A1HSP90AA1PKM
SCHEMBL14594696 0.74 LPL (0.44) HTTFAAHALDH1A1HSP90AA1PKM
SCHEMBL20180644 0.73 ALOX5 (0.48) MEN1MAPTKMT2A
SCHEMBL20180734 0.72 FAAH (0.32) HTTFAAHALDH1A1HSP90AA1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190051829-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2019-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190051829-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ORC3, BMP2, PPIP5K2 HTT 2754/4885FAAH 4024/4885ALDH1A1 2663/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.