Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21028746 | 0.77 | PLA2G7 (0.37) | PLA2G7CNR1CNR2GPR55LTA4H | |
| SCHEMBL20802902 | 0.74 | LTA4H (0.39) | CNR1CNR2GPR55LTA4HFFAR1 | |
| SCHEMBL12808277 | 0.74 | MMP12 (0.44) | FFAR1LMNA | |
| SCHEMBL21028857 | 0.73 | MAOA (0.57) | LTA4HTAAR1 | |
| SCHEMBL11767120 | 0.73 | ESR1 (0.52) | CNR1CNR2GPR55CYP3A4TP53 | |
| SCHEMBL20803450 | 0.72 | L3MBTL1 (0.65) | L3MBTL1CYP3A4CYP2C9TP53CYP1A2 | |
| SCHEMBL8095627 | 0.72 | LTA4H (0.53) | LTA4HFFAR1TSHRTAAR1 | |
| SCHEMBL20803493 | 0.70 | HDAC3 (0.62) | FFAR1CYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL7111320 | 0.68 | IGF1R (0.44) | CYP3A4CYP2C9CYP1A2TAAR1LMNA | |
| SCHEMBL10863097 | 0.68 | CALM1 (0.52) | LTA4HL3MBTL1CYP3A4CYP2C9TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925735-B1 | INHIBITORS OF SODIUM GLUCOSE COTRANSPORTER 1 | LEXICON PHARMACEUTICALS INC (US) | 2019-03-13 | — | — | EP | disclosed |