Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18458925 | 0.79 | L3MBTL1 (0.49) | L3MBTL1TDP1SIGMAR1 | |
| SCHEMBL20802895 | 0.77 | PLA2G7 (0.38) | PLA2G7LTA4HL3MBTL1TP53CYP1A2 | |
| SCHEMBL21028857 | 0.76 | MAOA (0.57) | LTA4HSLC5A1TAAR1HRH1 | |
| SCHEMBL11767120 | 0.76 | ESR1 (0.52) | TP53CYP3A4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20131148 | 0.75 | IDO1 (0.55) | L3MBTL1SLC6A2SLC6A4SLC6A3LMNA | |
| SCHEMBL20803450 | 0.74 | L3MBTL1 (0.65) | L3MBTL1TP53CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8095627 | 0.74 | LTA4H (0.53) | LTA4HTSHRTAAR1SLC6A2SLC6A4 | |
| SCHEMBL20749348 | 0.71 | TAAR1 (0.48) | CYP1A2CYP3A4CYP2C9TSHRTAAR1 | |
| SCHEMBL10863097 | 0.70 | CALM1 (0.52) | LTA4HL3MBTL1TP53CYP1A2CYP3A4 | |
| SCHEMBL20802902 | 0.70 | LTA4H (0.39) | LTA4HTSHRTAAR1CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489226-B1 | INHIBITORS OF SODIUM GLUCOSE COTRANSPORTER 1 | LEXICON PHARMACEUTICALS INC (US) | 2021-02-17 | — | — | EP | disclosed |
| EP-3489226-A1 | INHIBITORS OF SODIUM GLUCOSE COTRANSPORTER 1 | Lexicon Pharmaceuticals, Inc. (US) | 2019-05-29 | — | — | EP | disclosed |